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Funding Opportunity Number: PA-25-249. Assistance Listing: 93.273,93.279,93.847,93.855. Funding Instrument: G. Category: ED,FN,HL.
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Or search similar grants →According to the current listing, eligibility includes: Eligible applicants: State governments; County governments; City or township governments; Special district governments; Independent school districts; Public and State controlled institutions of higher education; Native American tribal governments (Federally recognized); Public housing authorities / Indian housing authorities; Native American tribal organizations (other than Federally recognized); Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Private institutions of higher education; For-profit organizations other than small businesses; Small businesses; Others (see text field entitled Additional Information on Eligibility for clarification). Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Confirm the full requirements in the official notice before applying.
The published deadline was March 10, 2025, which has passed. Check the official notice for any future application windows before investing time in a proposal.
Yes — NIAID, NIDDK, NIDA, and NIAAA Research Opportunities for New and "At-Risk" Investigators (R01 Clinical Trial Optional) is offered by National Institutes of Health and this listing comes from Grants.gov, an official U.S. federal source. Federal applications generally require registrations (for example SAM.gov or an agency submission portal), so allow extra lead time.
This opportunity targets applicants in Alaska and Hawaii. Check the official notice for exact location requirements.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
Past winners and funding trends for this program
PAR-23-298 is a grant from the National Cancer Institute and multiple NIH institutes that funds intervention research to improve Native American health. The program supports R01-level research projects including clinical trials aimed at addressing health disparities and chronic disease burdens in Native American communities, covering areas such as cardiovascular disease, aging, substance use, mental health, dental health, environmental health, and more. Participating institutes include NHLBI, NIA, NIDA, NIAAA, NIAID, NIAMS, NIBIB, NIDCD, NIDCR, NICHD, NIDDK, NIEHS, NIMH, NINR, NIMHD, NLM, and NCI. Both US and non-US organizations are eligible. Award amounts vary; the deadline for submissions is January 8, 2027. Note: this notice has expired and applications may be accepted on a case-by-case basis.
PA-23-317 is a grant from the National Institutes of Health (NIH) that funds competing revisions and administrative supplements to existing NIH single-project research grants and cooperative agreements. The program supports researchers who need to expand the scope or add new dimensions to active NIH-funded projects, with clinical trial components optional. Eligible applicants are current NIH grant recipients at participating institutes including NIAID, NIMH, NCI, NIDDK, NICHD, NIDA, NIEHS, and others. Applicants must have an active single-project research grant or cooperative agreement, and competing revision notices of special interest from individual institutes specify eligible activity codes.
PA-27-037 consolidates the Predoctoral to Postdoctoral Transition Award into a single parent announcement across 20 NIH components, with the next deadline December 8, 2026. The eligibility gate is not the science — it is a mandatory change of institution and mentor between the F99 and K00 phases.
Read articleA draft executive order would have put OMB Director Russell Vought on a commission with final say over NIH awards after peer review. Sen. Collins killed it by pointing at a provision Congress already passed. Here is what the episode teaches applicants about the December 11 cliff.
Read articlePA-27-034, PA-27-035 and PA-27-036 replace the institute-specific R25 announcements that research education programs have been built around for a decade. NCI, NIDA and NIGMS have already expired theirs early. Here is what the consolidation actually changes: an 8% indirect cost ceiling, a US-citizens-and-permanent-residents participant rule, a cooperative agreement variant that only exists on one of the three, and no clinical-trial-allowed companion anywhere.
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