Maui County 2026 Recycling Grants Program is sponsored by Maui County, Hawaii. County-level Hawaii grants for landfill diversion projects including recycling and waste reduction. Supports local nonprofits and community organizations working on plastic reduction and recycling infrastructure in Maui County.

Native Hawaiian Health Scholarship Program (NHHSP) is sponsored by Health Resources and Services Administration (HRSA). Provides financial support for Native Hawaiian students in health professions schools who commit to serving the Native Hawaiian population in Hawaii.

Atherton Family Foundation: Environmental Program and Capital Grants is sponsored by Atherton Family Foundation. Supports environmental programs and capital equipment (such as drones/sensors) that benefit the people of Hawai‘i; requires a 1:1 match for technology-related requests.

Holomua Marine Initiative: Laulima Grants is a grant from the Hawaii Community Foundation that funds Hawaii-based nonprofit organizations working to advance effective management of nearshore marine areas through community co-management and stewardship. The program supports collaborative projects that contribute to measurable progress toward well-managed coastal and marine ecosystems in Hawaii, with an emphasis on community-led approaches and collective impact. Organizations with annual budgets under $500,000 may apply for up to $50,000; organizations with budgets of $500,000 or more may request up to $150,000. The deadline for the current cycle is April 1, 2026. Eligible applicants are Hawaii-based nonprofits with demonstrated ties to nearshore marine conservation.

BOR Small Surface Water and Groundwater Storage Projects (Small Storage Program) is sponsored by U.S. Bureau of Reclamation (Department of Interior). Supports planning, design, or construction of small surface water and groundwater storage projects to improve water supply and community resilience.

SFCA Outreach Initiative Program is sponsored by Hawaii State Foundation on Culture and the Arts (SFCA). This program supports regional touring and outreach activities that increase opportunities for individuals to experience different forms of artistic and cultural expression and engagement in Hawaiʻi. The program aims to serve underserved communities across at least three islands. Activities should occur in public spaces, senior centers, public libraries, public housing communities, or a hybrid of online/streaming.

Undergraduate Education Program is a grant from W M Keck Foundation that funds distinctive learning and research experiences for undergraduates at colleges in designated Western states. The program supports innovative pedagogical approaches in the sciences, engineering, and liberal arts, emphasizing undergraduate research opportunities and hands-on engagement with faculty. Eligible applicants are undergraduate institutions located in Alaska, Arizona, California, Colorado, Hawaii, Idaho, Montana, Nevada, New Mexico, Oregon, Utah, Washington, or Wyoming. Applications are due May 1, 2026.

Undergraduate Education Program is sponsored by W M Keck Foundation. Promotes distinctive learning and research experiences in science, engineering, and the liberal arts. The program focuses on enhancing undergraduate research and fostering innovative pedagogy. Geographic focus: Designated Western States Focus areas: Undergraduate Education, STEM Education, Liberal Arts

The purpose of this Notice of Funding Opportunity (NOFO) is tofurther elucidate the mechanisms of early immune development in utero, during the early post-natal period and during early childhood in neonates, infants, and children and adolescents with or without in-utero exposure to HIV or Anti-Retroviral Therapeutics (ART).This initiative aims to understand intricate mechanisms of immune cells at the maternal-fetal interface, T and B cell development and maturation in offspring, and local immune responses and the role of systemic immunity. Funding Opportunity Number: PAR-25-362. Assistance Listing: 93.865. Funding Instrument: G. Category: HL,ISS. Award Amount: Up to $400K per award.

The Office of Research Infrastructure Programs (ORIP) within the Division of Program Coordination, Planning, and Strategic Initiatives announces an opportunity to apply for small grant support for ORIP-supported Special Emphasis Research Career Award (SERCA) K01 recipients who have completed the first two years (24 months) of the SERCA K01 award. ORIP seeks to enhance the ability of ORIP SERCA K01 awardees to conduct research as they transition to fully independent investigator status. The R03 mechanism supports projects including pilot and feasibility studies; secondary analysis of existing data; small, self-contained research projects; development of research methodology; and development of new research technology. The R03 is intended to support research projects that can realistically be completed in two years and that require limited levels of funding. This Funding Opportunity Announcement does not accept applications proposing clinical trial(s). Funding Opportunity Number: PAR-25-176. Assistance Listing: 93.351. Funding Instrument: G. Category: HL. Award Amount: Up to $75K per award.

This notice of funding opportunity (NOFO) encourages formative research, intervention development, and pilot-testing of interventions. Primary scientific areas of focus include the feasibility, tolerability, acceptability and safety of novel or adapted interventions that target HIV prevention, treatment or services research for people who use drugs. For the purposes of this NOFO, "intervention" may include behavioral, social, or structural approaches, as well as combination biomedical and behavioral approaches that prevent the acquisition and transmission of HIV infection, or improve clinical outcomes for persons living with HIV. Funding Opportunity Number: PAR-24-329. Assistance Listing: 93.279. Funding Instrument: G. Category: ED,HL.

The Native American Graves Protection and Repatriation Act of 1990 authorizes the Secretary of the Interior to make grants to museums, Indian Tribes, and Native Hawaiian organizations for the purposes of assisting in consultation, documentation, and repatriation of Native American human remains, funerary objects, sacred objects, and objects of cultural patrimony (25 U.S.C. 3008). NAGPRA Repatriation grants assist museums, Indian Tribes, and NHOs to defray costs associated with the packaging, transportation, contamination removal, reburial, and/or storage of NAGPRA human remains or cultural items. Project activities may include, but are not limited to:Travel,Transportation,Testing or decontamination,Building containers for transport,Ceremonial materials, orStaff time.See Program Overview for more details on project activities. Funding Opportunity Number: P25AS00474. Assistance Listing: 15.922. Funding Instrument: G. Category: O. Award Amount: $1K – $25K per award.

The NEI uses UG1 cooperative agreement awards to support investigator-initiated large-scale clinical trials, human gene-transfer, stem cell therapy trials, and other complex or high resource- or safety-risk clinical trials. These projects are multifaceted and of high public health significance requiring clear delineation of study organization including roles and responsibilities and require careful performance oversight and monitoring. For purposes of this Notice of Funding Opportunity (NOFO), the proposed study must be intended to evaluate interventions aimed at screening, diagnosing, preventing, or treating vision disorders, or to compare the effectiveness of two or more established interventions. The NEI UG1-supported studies are typically funded as a group of single-component companion grant awards including the Chairs Grant, the Coordinating Center, and Resource Centers, when appropriate. Specifically, this NOFO encourages applications for the Resource Center grant which provides imaging, laboratory, or other requisite services for a multi-center clinical trial or other complex or high-risk clinical trial. Funding Opportunity Number: PAR-23-201. Assistance Listing: 93.867. Funding Instrument: CA. Category: HL.

The NEI uses UG1 cooperative agreement awards to support investigator-initiated large-scale clinical trials, human gene-transfer, stem cell therapy trials, and other complex or high resource- or safety-risk clinical trials. These projects are multifaceted and of high public health significance requiring clear delineation of study organization including roles and responsibilities and require careful performance oversight and monitoring. For purposes of this Notice of Funding Opportunity (NOFO), the proposed study must be intended to evaluate interventions aimed at screening, diagnosing, preventing, or treating vision disorders, or to compare the effectiveness of two or more established interventions. The NEI UG1-supported studies are typically funded as a group of single-component companion grant awards including the Chairs Grant, the Coordinating Center, and Resource Centers, when appropriate. Specifically, this NOFO encourages applications for the Chair's grant, which includes the scientific rationale, study aims and significance of the research project. Funding Opportunity Number: PAR-23-209. Assistance Listing: 93.867. Funding Instrument: CA. Category: HL.

This Notice of Funding Opportunity Announcement (NOFO) solicits resource grant applications for projects that will provide accurate, useful, usable, and understandable health information to populations that experience health disparities and their health care providers. This NOFO supports the development of resources that can be used to improve health and well-being and that lead to reductions in health disparities. Access to accurate, useful, usable, and understandable health information is an important factor when managing health and health care. Proposed projects should harness the capabilities of information technology and medical or health libraries to disseminate clear, evidence-based health-related information in formats used by individuals and their health care providers. Proposed projects should emphasize the development and deployment of new information resources or services, or expand and improve an existing resource or service, to meet the needs of populations experiencing health disparities and to promote health access for all. Funding Opportunity Number: PAR-24-281. Assistance Listing: 93.313,93.879. Funding Instrument: G. Category: ED,HL. Award Amount: Up to $200K per award.

Through this Funding Opportunity Announcement (FOA), the National Cancer Institute (NCI) invites applications for investigator-initiated Program Project (P01) applications. The proposed Program may address any of the broad areas of cancer research, including (but not limited to) cancer biology, cancer prevention, cancer diagnosis, cancer treatment, and cancer control. Basic, translational, clinical, and/or population-based studies in all of these research areas are appropriate. Each application submitted in response to this FOA must consist of at least three research projects and an Administrative Core. The projects must share a common central theme, focus, and/or overall objective. Funding Opportunity Number: PAR-23-059. Assistance Listing: 93.393. Funding Instrument: G. Category: ED,HL.

The NIH Office of Research on Women's Health (ORWH) and participating NIH Institutes and Centers invite institutional career development award applications for Building Interdisciplinary Research Careers in Women's Health (BIRCWH) Career Development Programs, hereafter termed "Programs". Programs will support mentored research career development of junior faculty members, known as BIRCWH Scholars, who have recently completed clinical training or postdoctoral fellowships, and who will be engaged in interdisciplinary basic, translational, behavioral, clinical, and/or health services research relevant to the health of women and, where appropriate, the use of both sexes to better understand the influence of sex as a biological variable on health and disease. This Funding Opportunity Announcement (FOA) allows appointment of Scholars (K12) proposing to serve as the lead investigator of an independent clinical trial; or proposing a separate ancillary clinical trial; or proposing to gain research experience in a clinical trial led by another investigator, as part of their research and career development. Funding Opportunity Number: RFA-OD-24-013. Assistance Listing: 93.121,93.273,93.279,93.313,93.398,93.846,93.855,93.866. Funding Instrument: G. Category: ED,HL. Award Amount: Up to $840K per award.

The purpose of this NOFO is to support the creation of standards and related efforts that will allow researchers to easily access data from personal tracking devices. The awardees will be expected to partner with device manufacturers as well as the researcher community if the effort is going to be successful. It is expected that the awardees will create standards for personal tracking device data that serve the same purpose as the DICOM or Neuroimaging Informatics Technology Initiative (NIfTI) formats and standards do for medical image files. Funding Opportunity Number: PAR-24-250. Assistance Listing: 93.242. Funding Instrument: G. Category: HL.

The goal of this concept is to increase the impact of the BRAIN Initiative by targeted dissemination and integration of validated BRAIN Initiative tools to investigators at institutions that historically have not been major recipients of NIH support. This will be accomplished by awards to PIs at resource-limited institutions (RLIs) who pair with BRAIN technologists to facilitate training and adoption of BRAIN Initiative technologies in the recipient laboratories. Goals include two-way knowledge transfer between the PI and BRAIN technologist and to increase the participation of PIs at RLIs in BRAIN Initiative relevant research. Funding Opportunity Number: RFA-NS-25-016. Assistance Listing: 93.173,93.213,93.242,93.273,93.279,93.286,93.853,93.865,93.866,93.867. Funding Instrument: G. Category: ED,HL,ISS.

The purpose of this proposed Notice of Funding Announcement (NOFO) is to support development of biomarkers or clinical outcomes derived from digital health technology (DHT) for use in clinical trials for remote monitoring as primary or secondary endpoints. To improve clinical impact, increase statistical feasibility, and promote standardization, applicants will be expected to develop and test the digitally derived assessments in populations from at least three different diseases or conditions. Partnerships with non-profit patient advocacy organizations will be required. Funding Opportunity Number: PAR-25-170. Assistance Listing: 93.399,93.853,93.866. Funding Instrument: CA. Category: ED,HL.

This BRAIN Initiative Notice of Funding Opportunity (NOFO) is to support scaled reagent production and distribution facilities involving technologies to access brain cell types. Facilities for production and distribution of these reagents by a broad set of neuroscientists will be encouraged. This NOFO is part of the BRAIN Initiative Armamentarium for Brain Cell Access transformative project. Efforts will be supported to produce and distribute gene transfer, gene regulation, and genome engineering reagents for use in both genetically tractable and less tractable systems, including primates and human tissue, which are relevant for future translational efforts. Reagents to be produced and distributed are those designed and validated under other NOFOs from the Armamentarium transformative project. Funding Opportunity Number: RFA-MH-25-105. Assistance Listing: 93.173,93.213,93.242,93.273,93.279,93.286,93.853,93.865,93.866,93.867. Funding Instrument: CA. Category: ED,HL,ISS.

The Center for Inherited Disease Research (CIDR) high-throughput genotyping, sequencing and supporting statistical genetics services are designed to aid the identification of genes or genetic modifications that contribute to human health and disease or to enhance existing collections of well-phenotyped specimens in biorepositories by the addition of genotype or next-generation sequence data. The laboratory specializes in genomic services that cannot be efficiently carried out in individual investigator laboratories. CIDR provides the most up-to-date platforms, services and statistical genetic support. This is an NIH-wide initiative that is managed by NHGRI. Information about current services offered can be accessed via: http://www.cidr.jhmi.edu. Funding Opportunity Number: PAR-23-184. Assistance Listing: 93.113,93.121,93.172,93.399,93.853. Funding Instrument: G. Category: ED,ENV,HL.

The purpose of this Mentored Career Enhancement grant awards (K18) in Patient Centered Outcomes Research (PCOR) NOFO is to target established mid-career and senior investigators who are interested in developing new skills in comparative effectiveness research methodology and applying these methods to patient-centered outcome research (PCOR). Funding Opportunity Number: PA-22-051. Assistance Listing: 93.226. Funding Instrument: G. Category: HL.

Cooke Foundation: Environmental and Technology Grants is a grant from Cooke Foundation, Ltd. that funds nonprofit organizations in Hawai'i working to enhance community welfare with a focus on environmental protection and the use of technology to improve program efficiency or expand reach in conservation efforts. The foundation prioritizes projects that demonstrate meaningful impact in Hawaii's natural environment and leverage innovative technology solutions. Eligible applicants are 501(c)(3) nonprofit organizations based in or serving communities in Hawai'i. Specific award amounts and application deadlines are not publicly listed; nonprofits should contact the Cooke Foundation directly or review the foundation's grant-making criteria for current funding cycles and submission requirements.

The National Human Genome Research Institute (NHGRI) seeks to broaden the types of knowledge, skills, expertise, experience, and perspectives brought to bear in research addressing the ethical, legal and social implications (ELSI) of advances in human genetics or genomics. This Notice of Funding Opportunity (NOFO) solicits UM1 applications from domestic organizations located in the United States and its territories that received less than $30 million per year in total NIH funding for the past three fiscal years. These organizations are underrepresented among those receiving NHGRI funding for ELSI research. The Building Partnerships and Broadening Perspectives to Advance Ethical, Legal, and Social Implications (ELSI) Research (BPAER) Program will support: 1) transdisciplinary ELSI research addressing timely, complex, and understudied topics, 2) the establishment of research teams that include representatives from relevant communities who are affected by and have an interest in the proposed research, 3) research capacity building to develop, conduct and sustain ELSI research, and 4) workforce development opportunities for early career scholars, research team members, and other research project staff. Transdisciplinary ELSI research projects require involvement from two or more fields of knowledge and use of multiple research approaches. Relevant communities must be actively and meaningfully involved on ELSI research teams across all phases of proposed research projects. Research capacity building plans must be informed by a needs assessment. Given the complex structure, a strategic management plan, evaluation plan, and sustainability plan are required to ensure successful completion of the program. Funding Opportunity Number: RFA-HG-24-026. Assistance Listing: 93.172. Funding Instrument: CA. Category: HL. Award Amount: Up to $850K per award.

The purpose of the Resource-Related Research Projects (R24) grant is to support investigator-initiated resources designed to provide materials and services to support and advance biomedical research on a national basis. An R24 resource grant mechanism is a non-hypothesis-driven activity to provide data, materials, tools, or services that are essential to making timely, high quality, and cost-efficient progress in a field. Hypothesis-driven research applications should not be submitted in response to this program announcement but to another mechanism that encourages this type of research. The resource should be available to any qualified investigator, and should be highly quality controlled, and not duplicate resources available commercially or through other sources. Resources should be designed to provide services to the broad alcohol research community and should not be limited by any specific regional focus. Funding Opportunity Number: PAR-24-071. Assistance Listing: 93.273. Funding Instrument: G. Category: HL.

The Office of Research Infrastructure Programs (ORIP) invites grant applications from core facilities, resource centers, animal vivaria, or individual investigators of other shared resources to systematically study the roles of critical environmental extrinsic factors in biological, behavioral, and treatment studies using animal model species, with the objective of enhancing the rigor and reproducibility of animal research. The research area must be broadly applicable to the scientific interests of two or more NIH Institutes or Centers (ICs) and must evaluate the biological processes that impact multiple organ systems in order to align with the ORIPs NIH-wide mission and programs. The program supports the acquisition or update of modern equipment for measuring, monitoring, recording, and reporting environmental, biological or biobehavioral variables. The equipment requested must be capable of recording and reporting multiple parameters simultaneously. Funding Opportunity Number: PAR-24-167. Assistance Listing: 93.351. Funding Instrument: G. Category: HL.

Through this funding opportunity announcement (FOA), the National Cancer Institute (NCI) invites applications for P50 Research Center Grants for Specialized Programs of Research Excellence (SPORE). The program will fund P50 SPORE grants to support state-of-the-art investigator-initiated translational research that will contribute to improved prevention, early detection, diagnosis, and treatment of an organ-specific cancer or a highly related group of cancers. For the purpose of this FOA, a group of highly related cancers are those that are derived from the same organ system, such as gastrointestinal, neuroendocrine, head and neck, and other cancers. Other programmatically appropriate groups of cancers may include those centered around a common biological mechanism critical for promoting tumorigenesis and/or cancer progression in organ sites that belong to different organ systems. For example, a SPORE may focus on cancers caused by the same infectious agent or cancers promoted and sustained by dysregulation of a common signaling pathway. In addition, a SPORE may focus on cross-cutting themes such as pediatric cancers or cancer health disparities. The research supported through this program must be translational and must stem from research on human biology using cellular, molecular, structural, biochemical, and/or genetic experimental approaches. SPORE projects must have the goal of reaching a translational human endpoint within the project period of the grant. Funding Opportunity Number: PAR-23-284. Assistance Listing: 93.121,93.395. Funding Instrument: G. Category: ED,HL.

The goal of the NIGMS Predoctoral Basic Biomedical Sciences Research Training Program is to develop a pool of well-trained scientists available to address the Nations biomedical research agenda. Specifically, this funding opportunity announcement provides support to eligible, domestic institutions to develop and implement effective, evidence-informed approaches to biomedical graduate training and mentoring that will keep pace with the rapid evolution of the biomedical research enterprise. NIGMS expects that the proposed research training programs will incorporate didactic, research, and career development elements to prepare trainees for careers that will have a significant impact on the health-related research needs of the Nation. Funding Opportunity Number: PAR-23-228. Assistance Listing: 93.859. Funding Instrument: G. Category: HL.

This Notice of Funding Opportunity (NOFO) invites eligible academic or research institutions to apply for funding support to purchase latest scientific equipment that will enhance and modernize research-supporting operations of existing shared biomedical research facilities. Targeted are laboratory research core facilities, animal research facilities, and other similar shared-use research spaces. The goal of this NOFO is to strengthen research-auxiliary activities of biomedical research facilities and to enhance the efficiency of their operations. The NOFO does not support the purchase of scientific research instruments or their components, nor components of building-level infrastructure equipment that indirectly support research activities. Funding Opportunity Number: PAR-24-259. Assistance Listing: 93.351,93.859. Funding Instrument: G. Category: HL. Award Amount: Up to $350K per award.

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The overarching goal of this NIDCD R25 program is to support educational activities that help recruit individuals with specific specialty or disciplinary backgrounds to research careers in biomedical, behavioral and clinical sciences. Funding Opportunity Number: PAR-24-127. Assistance Listing: 93.173. Funding Instrument: G. Category: HL. Award Amount: Up to $500K per award.

The purpose of the NCI Pathway to Independence Award for Early-Stage Postdoctoral Researchers (K99/R00) program is to increase and maintain a strong cohort of new and talented, NCI-supported, independent investigators. This program is designed for postdoctoral fellows with research and/or clinical doctoral degrees who do not require an extended period of mentored research training beyond their doctoral degrees. The objective of this award is to facilitate a timely transition of these fellows from their mentored, postdoctoral research positions to independent tenure-track (or equivalent) faculty positions. The program will provide independent NCI research support during this transition to help awardees to launch competitive, independent research careers. Researchers in the scientific areas of cancer control, cancer prevention and cancer data sciences are especially encouraged to work with their institutions to apply. This notice of funding opportunity (NOFO) is designed specifically for candidates proposing to serve as the lead investigator of an independent clinical trial, a clinical trial feasibility study, or a separate ancillary clinical trial, as part of their research and career development. Those not planning an independent clinical trial, or proposing to gain research experience in a clinical trial led by another investigator, must apply to the 'Independent Clinical Trial Not Allowed' companion NOFO (PAR-23-286). Funding Opportunity Number: PAR-23-287. Assistance Listing: 93.398. Funding Instrument: G. Category: ED,HL.

The purpose of the NCI Pathway to Independence Award for Early-Stage Postdoctoral Researchers (K99/R00) program is to increase and maintain a strong cohort of new and talented, NCI-supported, independent investigators. This program is designed for postdoctoral fellows with research and/or clinical doctoral degrees who do not require an extended period of mentored research training beyond their doctoral degrees. The objective of this award is to facilitate a timely transition of these fellows from their mentored, postdoctoral research positions to independent tenure-track (or equivalent) faculty positions. The program will provide independent NCI research support during this transition to help awardees to launch competitive, independent research careers. Researchers in the scientific areas of cancer control, cancer prevention and cancer data sciences are especially encouraged to work with their institutions to apply. This notice of funding opportunity (NOFO) is for basic science experimental studies involving humans, referred to in NOT-OD-18-212 as prospective basic science studies involving human participants. These studies fall within the NIH definition of a clinical trial and also meet the definition of basic research. Types of studies that should be submitted under this NOFO include studies that prospectively assign human participants to conditions (i.e., experimentally manipulate independent variables) and that assess biomedical or behavioral outcomes in humans for the purpose of understanding the fundamental aspects of phenomena without specific application towards processes or products in mind. Those not planning an independent clinical trial or basic experimental study with humans, or proposing to gain research experience in a clinical trial or basic experimental study with humans led by another investigator, must apply to the 'Independent Clinical Trial Not Allowed' companion NOFO (PAR-23-286). Funding Opportunity Number: PAR-23-288. Assistance Listing: 93.398. Funding Instrument: G. Category: ED,HL.

The purpose of the NCI Pathway to Independence Award for Early-Stage Postdoctoral Researchers (K99/R00) program is to increase and maintain a strong cohort of new and talented, NCI-supported, independent investigators. This program is designed for postdoctoral fellows with research and/or clinical doctoral degrees who do not require an extended period of mentored research training beyond their doctoral degrees. The objective of this award is to facilitate a timely transition of these fellows from their mentored, postdoctoral research positions to independent tenure-track (or equivalent) faculty positions. The program will provide independent NCI research support during this transition to help awardees to launch competitive, independent research careers. Researchers in the scientific areas of cancer control, cancer prevention and cancer data sciences are especially encouraged to work with their institutions to apply. This Notice of Funding Opportunity (NOFO) is designed specifically for candidates proposing research that does not involve leading an independent clinical trial, a clinical trial feasibility study, or an ancillary clinical trial. Under this NOFO candidates are permitted to propose a research experience in a clinical trial led by a mentor or co-mentor. Those proposing a clinical trial or an ancillary clinical trial as lead investigator, should apply to the companion NOFOs (PAR-23-287 or PAR-23-288). Funding Opportunity Number: PAR-23-286. Assistance Listing: 93.398. Funding Instrument: G. Category: ED,HL.

This Funding Opportunity Announcement (FOA) invites applications for grant funding to conduct Large Research Projects (R01) focused on Combating Antibiotic-Resistant Bacteria (CARB) . Funding Opportunity Number: PA-22-047. Assistance Listing: 93.226. Funding Instrument: G. Category: HL.

The National Institutes of Health (NIH) hereby notifies NIH award recipients that funds may be available for revision applications to support the expansion of existing projects and/or programs within the awarding IC identified in the competitive revision Notice of Special Interest (NOSI). Applications for Revisions will be evaluated for scientific and technical merit by (an) appropriate Scientific Review Group(s), in accordance with NIH peer review policy and procedures, using the stated review criteria. Only applications submitted in response to a NOSI published by an NIH Institute or Center will be allowed to apply to this NOFO. Funding Opportunity Number: PA-23-317. Assistance Listing: 93.172,93.213,93.242,93.273,93.279,93.307,93.310,93.350,93.394,93.865,93.866,93.867. Funding Instrument: G. Category: ED,HL,ISS.

The purpose of this notice of funding opportunity (NOFO) is to provide salary support for exceptional Research Software Engineers (RSEs) that contribute their skills to the development and dissemination of biomedical, behavioral or health related software, tools, and algorithms as well as to the training of prospective users of these tools. Funding Opportunity Number: RFA-OD-24-011. Assistance Listing: 93.113,93.121,93.172,93.213,93.233,93.242,93.273,93.279,93.286,93.307,93.310,93.396,93.398,93.837,93.838,93.839,93.840,93.846,93.847,93.853,93.865,93.866,93.867,93.879. Funding Instrument: G. Category: ED,ENV,FN,HL,ISS.

This NOFO is a call to action in response to the mental health crisis in the United States. We seek applications that will study methods to increase access to evidence-based interventions and services for youth mental health, including those living in rural areas, inner cities, and other under-resourced areas, and youth experiencing housing and food insecurities and out-right homelessness. Applications should address research related to optimizing assessment, intervention and service strategies, overcoming challenges related to the workforce shortage, wait lists for treatment, integration of treatment and preventive interventions into settings where people are most likely to be best identified as needing care (eg: schools, social service, pediatric medicine and justice), and service interventions that address systemic barriers to access and quality of mental health care (structural, policy, organizational, value (cost/financing), management). Funding Opportunity Number: PAR-25-310. Assistance Listing: 93.242. Funding Instrument: G. Category: HL.

The purpose of this Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions is to support small scale research grants at institutions that do not receive substantial funding from the NIH, with an emphasis on providing biomedical research experiences primarily for undergraduate students and enhancing the research environment at applicant institutions.Eligible institutions must award baccalaureate science degrees and have received no more than $6 million dollars per year of NIH support (in both direct and F and A/indirect costs) in 4 of the last 7 fiscal years. For institutions composed of multiple schools and colleges, the $6 million funding limit is based on the amount of NIH funding received by all the non-health professional schools and colleges within the institution as a whole.This Notice of Funding Opportunity (NOFO) supports investigator-initiated mechanistic and/or minimal risk clinical trials addressing the mission and research interests of the participating NIH institutes. For the purpose of this NOFO, minimal risk clinical trials are defined as those that do not require FDA oversight, do not intend to formally establish efficacy, and have low risks to potentially cause physical or psychological harm. Funding Opportunity Number: PAR-24-214. Assistance Listing: 93.173,93.233,93.242,93.273,93.279,93.361,93.393,93.394,93.395,93.396,93.399,93.837,93.838,93.839,93.840,93.853,93.865,93.866,93.867. Funding Instrument: G. Category: ED,HL,ISS. Award Amount: Up to $375K per award.

The goal of the Medical Scientist Training Program (MSTP) is to develop a broad pool of highly trained physician-scientist leaders available to meet the needs of the Nations biomedical research agenda. Specifically, this Notice of Funding Opportunity (NOFO) provides support to eligible domestic institutions to develop and implement effective, evidence-based approaches to integrated dual-degree training leading to the award of both professional medical doctorate degrees and research doctorate degrees (Ph.D. or equivalent). With the dual qualification of rigorous scientific research and clinical practice, graduates will be equipped with the skills to develop research programs that accelerate the translation of research advances to the understanding, detection, treatment and prevention of human disease, and to lead the advancement of biomedical research. Areas of particular importance to NIGMS are the iterative optimization of MSTP training efficacy and efficiency, and fostering the persistence of MSTP alumni in research careers. NIGMS expects that the proposed research training programs will incorporate didactic, research, mentoring and career development elements to prepare trainees for careers that will have a significant impact on the health-related research needs of the Nation. Funding Opportunity Number: PAR-24-128. Assistance Listing: 93.859. Funding Instrument: G. Category: HL.

The Biomedical Research Environment and Sponsored Programs Administration Development (BRE-SPAD) Program aims to promote broad participation in the biomedical research ecosystem by supporting resource limited organizations to conduct research, enhance the research environment, and increase sponsored programs administration capacity.This program intends to support eligible, domestic organizations with limited research resources and few biomedical doctoral students. Funding Opportunity Number: PAR-24-268. Assistance Listing: 93.121,93.213,93.242,93.273,93.279,93.310,93.846,93.853,93.859,93.866,93.867. Funding Instrument: CA. Category: ED,HL. Award Amount: Up to $500K per award.

Awarded activities will facilitate the translation of novel recording and modulation technologies that can be used to treat and/or diagnose central nervous system (CNS) diseases and disorders and to better understand the human CNS, from proof of concept up to the stage of readiness for first in human (FIH) studies. Technologies may incorporate any signal modality (e.g., electrical, optical, magnetic, acoustic) or a combination thereof. Diverse team-based applications that integrate appropriate domains of expertise are encouraged. Funding Opportunity Number: RFA-NS-24-031. Assistance Listing: 93.173,93.213,93.242,93.273,93.279,93.286,93.853,93.865,93.866,93.867. Funding Instrument: G. Category: ED,HL,ISS. Award Amount: Up to $750K per award.

The purpose of the Worta McCaskill-Stevens K12 funding opportunity is to support institutional career development awards designed to prepare newly trained clinicians who have made a commitment to independent research careers in community oncology or cancer prevention, and to facilitate their transition to more advanced support mechanisms or independent research funding (e.g., K08, R03, R21, R01).The NOFO will allow the appointment of Scholars proposing to serve as the lead investigator of an independent community-based clinical trial; or proposing a separate ancillary study to an existing prevention, screening or control clinical trial; or proposing to gain research experience in a community-based clinical trial led by another investigator; or proposing to serve as leader of innovative clinical trial approaches that expand engagement of a wide variety of communities in cancer clinical research, as part of their research and career development. Funding Opportunity Number: PAR-24-153. Assistance Listing: 93.398,93.399. Funding Instrument: G. Category: ED,HL.

The AHRQ Small Research Grant Program supports small research projects that can be carried out in a short period of time with limited resources. This program supports different types of projects including pilot and feasibility studies; secondary analysis of existing data; small, self-contained research projects; development of research methodology; and development of new research technology. Funding Opportunity Number: PA-23-115. Assistance Listing: 93.226. Funding Instrument: G. Category: HL.

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The overarching goal of this R25 program is to support educational activities that complement and/or enhance the training of a workforce to meet the nations biomedical, behavioral and clinical research needs. To accomplish the stated over-arching goal, this FOA will support creative educational activities with a primary focus on: Courses for Skills Development Funding Opportunity Number: RFA-OD-25-003. Assistance Listing: 93.121,93.173,93.213,93.233,93.242,93.279,93.313,93.361,93.398,93.837,93.838,93.839,93.840,93.847. Funding Instrument: G. Category: ED,FN,HL. Award Amount: Up to $200K per award.

This Notice of Funding Opportunity Announcement (NOFO) invites grant applications for Environmental Health Sciences Core Centers (EHSCC). As intellectual hubs for environmental health science research, the EHSCC's are expected to be the thought leaders for the field and advance the goals of the 2025-2029 NIEHS Strategic Plan (http://www.niehs.nih.gov/about/strategicplan/). The Core Centers provide critical research infrastructure, shared facilities, services and/or resources, to groups of investigators conducting environmental health sciences research. An EHSCC enables researchers to conduct their independently-funded individual and/or collaborative research projects more efficiently and/or more effectively. The overall goal of an EHSCC is to identify and capitalize on emerging issues that advance improving the understanding of the relationships among environmental exposures, human biology, and disease. The EHSCC supports community engagement and translational research as key approaches to improving public health. Funding Opportunity Number: RFA-ES-25-002. Assistance Listing: 93.113. Funding Instrument: G. Category: ENV,HL.

The purpose of the NIDCD Mentored Career Development Award for Postdoctorate Au.D./Ph.D. Audiologists (K01) is to support comprehensive and rigorous postdoctoral research and career development experiences in the biomedical, behavioral, or clinical sciences of promising Au.D./Ph.D. audiologists who have the potential to become productive, independent investigators in scientific health-related research fields relevant to NIDCD's mission. Funding Opportunity Number: PAR-24-149. Assistance Listing: 93.173. Funding Instrument: G. Category: HL.

The purpose of the NIDCD Mentored Career Development Award for Postdoctorate Au.D./Ph.D. Audiologists (K01) is to support comprehensive and rigorous postdoctoral research and career development experiences in the biomedical, behavioral, or clinical sciences of promising Au.D./Ph.D. audiologists who have the potential to become productive, independent investigators in scientific health-related research fields relevant to NIDCD's mission. Funding Opportunity Number: PAR-24-159. Assistance Listing: 93.173. Funding Instrument: G. Category: HL.

The purpose of the NIDCD Research Career Enhancement Award for Established Investigators (K18) program is to enable established, proven investigators to augment or redirect their research programs through the acquisition of new research skills to answer questions relevant to the hearing, balance, smell, taste, voice, speech and language sciences. Funding Opportunity Number: PAR-24-143. Assistance Listing: 93.173. Funding Instrument: G. Category: HL.

The purpose of this initiative is to advance the science of minority health and health disparities by supporting research on family health and well-being and resilience. The NIMHD Research Framework recognizes family health, family well-being, and family resilience as critically important areas of research to decrease disparities and promote equity. Funding Opportunity Number: PAR-25-317. Assistance Listing: 93.273,93.307,93.310,93.313,93.361,93.399. Funding Instrument: G. Category: ED,HL.

The purpose of this NOFO is to invite grant applications that support healthcare safety by determining (1) whether and how certain breakthrough uses of Artificial Intelligence (AI) systems can affect patient safety; and (2) how AI systems can be safely implemented and used. AI has the potential to improve the safety, effectiveness, efficiency, accessibility, and affordability of healthcare. However, as with most technologies, this potential must be balanced by identifying and mitigating potential risks for patient harm and user burden. Funding Opportunity Number: PA-24-261. Assistance Listing: 93.226. Funding Instrument: G. Category: HL.

This Notice of Funding Opportunity Announcement (NOFO) from the NIH Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative is intended to support establishment of facilities at minority-serving institutions (MSIs) and Institutional Development Award (IDeA)-eligible institutions for scaled production and distribution of brain cell type-specific access and manipulation reagents. Reagents will be initially developed in pilot resource projects for brain cell type-specific access and manipulation across vertebrate species from the BRAIN Initiative Armamentarium project. Awardees under this NOFO will work with the other Armamentarium awardees to manufacture and distribute the resources for use throughout the neuroscience community. It is envisioned that the awardees will work both with the Armamentarium community as well as with the neuroscience research community to optimize the use of new reagents. The types of reagents to be produced and distributed could include but are not limited to viral vectors, nucleic acid constructs, and nanoparticles designed for selective access to and manipulation of brain cell types. Such reagents will enable neuroscientists to probe circuit function with high precision in experimental animals and ex vivo human tissue and cells. Facilities are needed to contribute to the production and distribution of BRAIN Initiative Armamentarium project reagents broadly to neuroscience users. Funding Opportunity Number: RFA-MH-26-120. Assistance Listing: 93.173,93.213,93.242,93.273,93.279,93.286,93.853,93.865,93.866,93.867. Funding Instrument: CA. Category: ED,HL,ISS.

This NOFO solicits applications for next generation sensor and bioelectronic device development that will synchronize with brain recordings. The sensor and neural recording data will be used to generate new computational models of behavior in human and animal models. There has been a lack of quantitative approaches and models to understand the complexity of human and animal behavior in naturalistic settings. This NOFO focuses on the development of next generation sensors to acquire data and synchronize it with simultaneous brain recordings to build computational models. Funding Opportunity Number: RFA-MH-26-140. Assistance Listing: 93.173,93.213,93.242,93.273,93.286,93.853,93.865,93.866,93.867. Funding Instrument: CA. Category: HL,ISS.

The purpose of this funding opportunity announcement (FOA) is to invite applications for a broad range of research efforts in computational genomics, data science, statistics, and bioinformatics relevant to one or both of basic or clinical genomic science, and broadly applicable to human health and disease. This FOA supports fundamental genomics research developing innovative analytical methodologies and approaches, early-stage development of tools and software, and refinement or hardening of software and tools of high value to the biomedical genomics community. Work supported under this FOA should be enabling for genomics and be generalizable or broadly applicable across diseases and biological systems. All applications should address how the methods would scale to address increasingly larger data sets. Funding Opportunity Number: PAR-25-229. Assistance Listing: 93.172,93.879. Funding Instrument: G. Category: ED,HL.

The purpose of this funding opportunity announcement (FOA) is to invite applications for a broad range of research efforts in computational genomics, data science, statistics, and bioinformatics relevant to one or both of basic or clinical genomic science, and broadly applicable to human health and disease. This FOA supports fundamental genomics research developing innovative analytical methodologies and approaches, early-stage development of tools and software, and refinement or hardening of software and tools of high value to the biomedical genomics community. Work supported under this FOA should be enabling for genomics and be generalizable or broadly applicable across diseases and biological systems. All applications should address how the methods would scale to address increasingly larger data sets. Funding Opportunity Number: PAR-25-228. Assistance Listing: 93.172,93.879. Funding Instrument: G. Category: ED,HL.

This Notice of Funding Opportunity (NOFO) will support pilot, feasibility or exploratory research in 5 priority areas in substance use epidemiology and health services, including: 1) responses to sudden and severe emerging drug issues (e.g. the ability to look into a large and sudden spike in opioid or synthetic cannabinoid use/overdoses in a particular community); 2) responses to emerging marijuana trends and topics related to the shifting policy landscape; 3) responses to unexpected and time-sensitive prescription drug abuse research opportunities (e.g., new state or local efforts); 4) responses to unexpected and time-sensitive medical system issues (e.g. opportunities to understand addiction services in the evolving health care system); and 5) responses to unexpected and time-sensitive criminal or juvenile justice opportunities (e.g. new system and/or structural level changes) that relate to drug abuse and access and provision of health care service. It should be clear that the knowledge gained from the proposed study is time-sensitive and that an expedited rapid review and funding are required in order for the scientific question to be answered (i.e. an imminent policy change will not allow for standard review and funding timeline). Funding Opportunity Number: PAR-24-298. Assistance Listing: 93.279. Funding Instrument: G. Category: ED,HL.

The purpose of this Notice of Funding Opportunity (NOFO) is to support the continued operation, maintenance, and dissemination of unique database bioinformatics resources that are of major importance to the research community using animal models of embryonic developmental processes. These grants will support ongoing development and enhancement of the resources, user training and services, provision of community generated data storage and curation, wide dissemination of the tools and/or resources, and expansion of interoperability with other NIH bioinformatics resources. Funding Opportunity Number: PAR-24-301. Assistance Listing: 93.865. Funding Instrument: G. Category: HL,ISS.

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The overarching goal of this R25 program is to support educational activities that help recruit individuals with specific specialty or disciplinary backgrounds to research careers in biomedical, behavioral and clinical sciences. Funding Opportunity Number: PAR-25-020. Assistance Listing: 93.173. Funding Instrument: G. Category: HL. Award Amount: Up to $250K per award.

This Funding Opportunity Announcement (FOA) is intended to provide an avenue for basic scientists, clinicians and clinical scientists to jointly initiate and conduct translational research projects which translate basic research findings into clinical tools for better human health. The scope of this FOA includes a range of activities to encourage translation of basic research findings which will impact the diagnosis, treatment and prevention of communication disorders. Connection to the clinical condition must be clearly established and the outcomes of the grant must have practical clinical impact. Funding Opportunity Number: RFA-DC-25-002. Assistance Listing: 93.173. Funding Instrument: G. Category: HL. Award Amount: Up to $500K per award.

The purpose of the NCI Pathway to Independence Award (K99/R00) program is to facilitate a timely transition of talented postdoctoral researchers with a research and/or clinical doctorate degree from mentored, postdoctoral research positions to independent, tenure-track or equivalent faculty positions. The program will provide independent NCI research support during this transition in order to help awardees to launch competitive, independent research careers. Funding Opportunity Number: PAR-25-135. Assistance Listing: 93.398. Funding Instrument: G. Category: ED,HL.

The purpose of the NCI Pathway to Independence Award (K99/R00) program is to facilitate a timely transition of talented postdoctoral researchers with a research and/or clinical doctorate degree from mentored, postdoctoral research positions to independent, tenure-track or equivalent faculty positions. The program will provide independent NCI research support during this transition in order to help awardees to launch competitive, independent research careers. Funding Opportunity Number: PAR-25-313. Assistance Listing: 93.398. Funding Instrument: G. Category: ED,HL.

NIMH requires an experimental therapeutics approach for the development and testing of therapeutic interventions, in which studies both evaluate the clinical effect of an intervention and generate information about the mechanisms underlying a disorder or an intervention response. As part of NIMHs Clinical Trial Pipeline, this NOFO encourages early stage testing of pharmacologic interventions with novel mechanisms of actions or device-based interventions. More specifically, this NOFO is intended to support early stage testing of pharmacologic or device-based interventions using a protocol design where the presumed mechanism of action of the intervention is adequately tested, to provide meaningful information where target modulation yields a dose-dependent neurophysiological/clinical/behavioral effect. Funding Opportunity Number: PAR-25-184. Assistance Listing: 93.242. Funding Instrument: G. Category: HL.

NIMH requires an experimental therapeutics approach for the development and testing of therapeutic interventions, in which studies both evaluate the clinical effect of an intervention and generate information about the mechanisms underlying a disorder or an intervention response. As part of NIMHs Clinical Trial Pipeline, this NOFO encourages early stage testing of pharmacologic interventions with novel mechanisms of actions or device-based interventions. More specifically, this NOFO is intended to support early stage testing of pharmacologic or device-based interventions using a protocol design where the presumed mechanism of action of the intervention is adequately tested, to provide meaningful information where target modulation yields a dose-dependent neurophysiological/clinical/behavioral effect. Funding Opportunity Number: PAR-25-183. Assistance Listing: 93.242. Funding Instrument: G. Category: HL.

Pilot Effectiveness Trials for Treatment, Preventive and Services Interventions (R01 Clinical Trial Required). As part of NIMH's clinical trials pipeline NOFOs, this announcement encourages pilot effectiveness studies focused on 1) optimizing the effectiveness of preventive and therapeutic interventions with previously demonstrated efficacy, for use with broader target populations or for use in community practice settings, and 2) developing and preliminary testing innovative services interventions. Consistent with the NIMH experimental therapeutics approach, this NOFO is intended to support pilot studies of intervention effectiveness or service delivery approaches that explicitly address whether the intervention engages the target(s)/mechanism(s) presumed to underlie the intervention effects (i.e., the mechanism(s) that accounts for changes in clinical/functional outcomes, changes in provider behavior, improved access or continuity of services, etc.). Funding Opportunity Number: PAR-25-178. Assistance Listing: 93.242. Funding Instrument: G. Category: HL.

This R61/R33 concept complements NIMHs suite of clinical trial NOFOs by supporting feasibility and infrastructure development (R61) followed by well-powered clinical trials (R33) to test the effectiveness of system interventions and strategies for improving the organization, delivery, coordination, and clinical and functional outcomes of mental health services. System interventions - which may span, for example, structural, policy, organizational, and interpersonal domains - attend to issues about the access, equity, engagement/utilization, value (cost/financing), management, or quality and safety of mental health services, with the goal of improved care processes and clinical and functional outcomes. Accordingly, the focus of system interventions may include a variety of care settings, such as health systems and organizations, mental health and community clinics, schools, and child welfare or juvenile justice systems Funding Opportunity Number: PAR-25-285. Assistance Listing: 93.242. Funding Instrument: G. Category: HL.

The purpose of this Notice of Funding Opportunity (NOFO) is to encourage cooperative agreement applications to support early stage clinical trials of novel mechanism of action, investigational drugs, or novel neuromodulatory devices for the treatment of psychiatric disorders in areas of unmet medical need. The NOFO will support milestone-driven early stage trials in pediatric and adult populations. First in human (FIH) and Phase II studies of novel agents must assess target engagement (brain exposure), pharmacological effects, safety, and tolerability to assess feasibility for Phase II/proof of concept (PoC) studies in psychiatric disorders. Phase II/PoC studies must evaluate the drugs impact on clinically relevant physiological systems (functional measures) and clinical indicators of effect. The NOFO also supports FIH and early feasibility studies (EFS) of novel devices to evaluate target engagement, safety, tolerability, and efficacy. The overall objective is to facilitate rapid collection of data to "de-risk" novel mechanism of action investigational drugs, novel drugs for use in pediatric populations with psychiatric disorders, and devices or combination treatments in order to attract private or other public funding for further clinical development as FDA-approved treatments. A key aspect of this NOFO is the formation of collaborative partnerships between the biomedical researchers and biotechnology or industry researchers to facilitate psychiatric drug or device development. Funding Opportunity Number: PAR-25-180. Assistance Listing: 93.242. Funding Instrument: CA. Category: HL.

Clinical Trials to Test the Effectiveness of Treatment, Preventive, and Services Interventions (R01 Clinical Trial Required). This NOFO is a key element of NIMHs set of NOFOs to support clinical trials research across the intervention development and testing pipeline. The NOFO supports (1) clinical trials to test the effectiveness of optimized therapeutic and preventive interventions for use in community and practice settings; and (2) clinical trials to evaluate the effectiveness of patient-, provider-, organizational-, or systems-level services interventions to improve access, continuity, quality, equity, and/or value of mental health services. This NOFO is intended to support trials that: address a significant problem, such that the findings have potential to inform practice; are adequately powered to definitively answer the primary research question(s), with well-justified hypotheses supported by pilot data; and are designed to examine questions regarding mediators and moderators of effects. Consistent with the NIMH experimental therapeutics approach, this NOFO is intended to support effectiveness trials that explicitly address whether the intervention engages the target(s)/mechanism(s) presumed to underlie the intervention effects (i.e., the mechanism(s) that accounts for changes in clinical/functional outcomes, changes in provider behavior, improved access or continuity of services, etc.). The collaborative R01 mechanism provides support for multisite trials when two or more sites are necessary for completion of the trial (e.g., to increase sample size, accelerate recruitment, or increase sample diversity and representation). Funding Opportunity Number: PAR-25-177. Assistance Listing: 93.242. Funding Instrument: G. Category: HL.

Confirmatory Efficacy Clinical Trials of Non-Pharmacological Interventions for Mental Disorders (R01 Clinical Trial Required). As part of NIMH's clinical trials pipeline NOFOs, this announcement supports confirmatory efficacy testing of non pharmacological therapeutic and preventive interventions for mental disorders in adults and children that address unmet therapeutic needs, and are consistent with the NIMH emphasis on the experimental therapeutics approach. In this approach, clinical trials should be designed to increase knowledge of the relationship between underlying disease processes and the mechanisms of action through which any intervention produces therapeutic change. Funding Opportunity Number: PAR-25-179. Assistance Listing: 93.242. Funding Instrument: G. Category: HL.

Reissue of PAR-20-118. This Notice of Funding Opportunity (NOFO) encourages applications to advance the discovery, preclinical development, and proof of concept (PoC) testing of new, rationally based candidate agents and neurostimulation approaches to treat mental disorders, substance use disorders (SUDs) or alcohol use disorder (AUD), and to develop novel ligands and circuit-engagement devices as tools to further characterize existing or to validate new drug/device targets. Partnerships between academia and industry are strongly encouraged. This NOFO using the U01 mechanism supports a discrete, specified, circumscribed project to be performed by the named investigator(s) in an area representing his or her specific interest and competencies Projects seeking support for a research program of multiple projects directed toward a specific major objective, basic theme or program goal, requiring a broadly based, multidisciplinary and often long-term approach should consider the companion U19 FOA. Funding Opportunity Number: PAR-25-352. Assistance Listing: 93.242. Funding Instrument: CA. Category: HL.

The purpose of this Notice of Funding Opportunity (NOFO) is to leverage NICHD clinical research Network infrastructure relevant to infants, children, women, pregnant and lactating women, and persons with disabilities to conduct innovative, multisite, investigator-initiated clinical trials and observational studies. This NOFO will utilize a bi-phasic (UG3/UH3), milestone-driven mechanism consisting of a start-up phase (UG3) and a full enrollment and clinical trial implementation phase (UH3). Applications submitted in response to this NOFO must address specific aims and milestones for both the UG3 and UH3 phases. A UG3 project (phase I) that meets its milestones will be administratively considered by NICHD and prioritized for transition to the UH3 award (phase II). This NOFO provides an opportunity to leverage NICHD clinical research Network infrastructure as a platform for investigator-initiated innovative hypotheses by any investigator in the extramural community. Applications must be submitted as investigator-initiated, multi-Project Director/Principal Investigator (PD/PI) grant applications in conjunction with the respective NICHD-supported Network Data Coordinating Center (DCC), or equivalent as determined by the NICHD. Funding Opportunity Number: PAR-25-311. Assistance Listing: 93.313,93.865. Funding Instrument: CA. Category: HL,ISS. Award Amount: Up to $6.3M per award.

Through this Notice of Funding Opportunity (NOFO), entitled "Toward Translation of Nanotechnology Cancer Interventions" (TTNCI), the National Cancer Institute (NCI) encourages applications for advanced pre-clinical research, supporting translation of nanotechnology-based cancer diagnostics and therapeutics. TTNCI awards are designed to mature experimental nanomedicines relying on nanoparticles and nano-devices which demonstrate strong potential to improve cancer treatment effectiveness due to the combination of nanoparticle/nano-device structural design and/or therapeutic/diagnostic cargo which is delivered. TTNCI awards are expected to enable further development of proposed nanotechnology-based interventions to the stage in which they could continue on a developmental path towards the NCI Experimental Therapeutics (NExT) and other NCI translational programs. Funding Opportunity Number: PAR-25-336. Assistance Listing: 93.395. Funding Instrument: G. Category: ED,HL.

The purpose of this notice of funding opportunity (NOFO) is to invite applications proposing the innovative analysis of existing social science, behavioral, administrative, and neuroimaging data to study the etiology and epidemiology of drug using behaviors (defined as alcohol, tobacco, prescription and other drug) and related disorders, prevention of drug use and HIV, and health service utilization. This FOA encourages the analyses of public use and other extant community-based or clinical datasets to their full potential in order to increase our knowledge of etiology, trajectories of drug using behaviors and their consequences including morbidity and mortality, risk and resilience in the development of psychopathology, strategies to guide the development, testing, implementation, and delivery of high quality, effective and efficient services for the prevention and treatment of drug abuse and HIV. Funding Opportunity Number: RFA-DA-26-056. Assistance Listing: 93.273,93.279. Funding Instrument: G. Category: ED,HL.

The goal of the NHLBI Catalyze Program is to provide a comprehensive suite of support and services to facilitate the transition of basic science discoveries into viable diagnostic and therapeutic candidates that have been cleared for human testing, and to develop translational researchers fluent in product development and entrepreneurship. This specific Catalyze Product Definition initiative will provide the early stage translational support needed for prototype testing/design modification, assay development for diagnostic disease targets, and development of research tools for use in the treatment of HLBS diseases and disorders. Following successful completion of the program, it is expected that the potential products will be poised to move forward for in vivo testing (optimization, safety, efficacy) with additional support from NIH and/or other federal and private programs. This initiative has a companion initiative that supports development of therapeutics and combination products and is also part of a suite of innovation grants to advance projects to the point where they can meet the entry criteria for the NHLBI Catalyze Preclinical Program. Funding Opportunity Number: RFA-HL-26-020. Assistance Listing: 93.233,93.837,93.838,93.839. Funding Instrument: G. Category: HL.

The goal of the NHLBI Catalyze Program is to provide a comprehensive suite of support and services to facilitate the transition of basic science discoveries into viable diagnostic and therapeutic candidates that have been cleared for human testing, and to develop translational researchers fluent in product development and entrepreneurship. This specific Catalyze Product Definition initiative will provide the early stage translational support needed for the activities required to develop and test device prototypes, identify diagnostic disease targets and develop associated assays, and develop research tools to treat HLBS diseases and disorders. This is a phased initiative for early stage projects. The R61 phase provides support to identify and test initial prototype designs, to identify a disease target and generate experimental design, and to identify, test and pilot research tools. The R33 phase provides support for continued prototype development and testing, in addition to modifying design features and user feedback, diagnostic product generation, exploration of assay components, and characterization of a load design, and research tool improvement, large trial testing and data integration. Following successful completion of the program, it is expected that the potential products will be poised to move forward for in vivo testing (optimization, safety, efficacy) with additional support from NIH and/or other federal and private programs. This initiative has a companion initiative that supports development of therapeutics and combination products and is also part of a suite of innovation grants to advance projects to the point where they can meet the entry criteria for the NHLBI Catalyze Preclinical Program. Funding Opportunity Number: RFA-HL-26-019. Assistance Listing: 93.233,93.837,93.838,93.839. Funding Instrument: G. Category: HL.

The goal of the NHLBI Catalyze Program is to provide a comprehensive suite of support and services to facilitate the transition of basic science discoveries into viable diagnostic and therapeutic candidates that have been cleared for human testing, and to develop translational researchers fluent in product development and entrepreneurship. This specific Catalyze Product Definition initiative will provide the early stage translational support needed for the activities required to identify and characterize potential therapeutic candidates and combination products to treat HLBS diseases and disorders. This initiative has a companion initiative that supports development of devices and diagnostics and is also part of a suite of innovation grants to advance projects to the point where they can meet the entry criteria for the NHLBI Catalyze Preclinical Program. Funding Opportunity Number: RFA-HL-26-018. Assistance Listing: 93.233,93.837,93.838,93.839. Funding Instrument: G. Category: HL.

The goal of the NHLBI Catalyze Program is to provide a comprehensive suite of support and services to facilitate the transition of basic science discoveries into viable diagnostic and therapeutic candidates that have been cleared for human testing, and to develop translational researchers fluent in product development and entrepreneurship. This specific Catalyze Product Definition initiative will provide the early stage translational support needed for the activities required to identify and characterize potential therapeutic candidates and combination products to treat HLBS diseases and disorders. This initiative has a companion initiative that supports development of devices and diagnostics and is also part of a suite of innovation grants to advance projects to the point where they can meet the entry criteria for the NHLBI Catalyze Preclinical Program. Funding Opportunity Number: RFA-HL-26-017. Assistance Listing: 93.233,93.837,93.838,93.839. Funding Instrument: G. Category: HL.

To support competing renewal or competitive revision of ongoing clinical trials supported by the National Institute of Dental and Craniofacial Research (NIDCR) Funding Opportunity Number: PAR-25-062. Assistance Listing: 93.121. Funding Instrument: CA. Category: HL.

To support UG3/UH3 phased, cooperative agreement research applications to plan and implement clinical trials within the mission of the National Institute of Dental and Craniofacial Research (NIDCR) Funding Opportunity Number: PAR-25-057. Assistance Listing: 93.121. Funding Instrument: CA. Category: HL.

The NIH Exploratory/Developmental Grant supports exploratory and developmental research projects by providing support for the early and conceptual stages of these projects. These studies may involve considerable risk but may lead to a breakthrough in a particular area, or to the development of novel techniques, agents, methodologies, models, or applications that could have a major impact on a field of biomedical, behavioral, or clinical research. This Parent Notice of Funding Opportunity requires that at least 1 clinical trial be proposed. The proposed project must be related to the programmatic interests of one or more of the participating NIH Institutes and Centers (ICs) based on their scientific missions.Applicants should note that some ICs (see Related Notices) only accept applications proposing mechanistic studies that meet NIH's definition of a clinical trial through this funding opportunity announcement. Funding Opportunity Number: PA-25-306. Assistance Listing: 93.113,93.143,93.172,93.173,93.213,93.233,93.242,93.273,93.279,93.286,93.307,93.361,93.393,93.394,93.395,93.396,93.399,93.837,93.838,93.839,93.840,93.846,93.855,93.865,93.866,93.867,93.879. Funding Instrument: G. Category: ED,ENV,HL,ISS.

The overarching purpose of this Funding Opportunity Announcement (FOA) is to promote the discovery and/or early evaluation of strong candidate biomarkers and biomarker signatures that can be used as tools to facilitate the clinical development of neurotherapeutics and their use in clinical practice. Specifically, the focus of this FOA is on the identification and initial biological, analytical and clinical evaluation of biomarkers and biomarker signatures for neurological and neuromuscular disorders. Although research supported by this FOA can include animal studies, it must also include preliminary human evaluation using carefully standardized human samples or datasets. The goal of this initiative is to deliver candidate biomarkers or biomarker signatures that are ready for definitive analytical and clinical validation studies. Funding Opportunity Number: PAR-25-024. Assistance Listing: 93.853,93.866. Funding Instrument: G. Category: HL.

The NIH Exploratory/Developmental Grant supports exploratory and developmental research projects by providing support for the early and conceptual stages of these projects. These studies may involve considerable risk but may lead to a breakthrough in a particular area, or to the development of novel techniques, agents, methodologies, models, or applications that could have a major impact on a field of biomedical, behavioral, or clinical research. Funding Opportunity Number: PA-25-304. Assistance Listing: 93.113,93.121,93.143,93.172,93.173,93.213,93.233,93.242,93.273,93.279,93.286,93.307,93.310,93.361,93.393,93.394,93.395,93.396,93.399,93.837,93.838,93.839,93.840,93.846,93.855,93.865,93.866,93.867,93.879. Funding Instrument: G. Category: ED,ENV,HL,ISS.

This Notice of Funding Opportunity (NOFO) intends to support fundamental research that will contribute to basic understanding of skin injuries caused by chemicals that have been identified as public health threats, with an emphasis on investigating the commonalities of such injuries and identifying potential shared signaling pathways and therapeutic targets for medical countermeasure development. Funding Opportunity Number: PA-25-093. Assistance Listing: 93.846,93.855. Funding Instrument: G. Category: HL.

The Joint NINDS/NIMH Exploratory Neuroscience Research Grant program supports exploratory and innovative research projects, which fall within the missions of the NINDS and NIMH. Awards will provide support for the early and conceptual stages of projects. These studies often assess the feasibility of a novel avenue of investigation and involve considerable risk, but have the potential to bring about breakthroughs in the understanding of important areas of neuroscience, or to the development of novel techniques, agents, methodologies, or models, of high value to the neuroscience community. While this funding opportunity also accepts clinical trials, only applications proposing mechanistic clinical trials or studies or basic experimental studies with humans (BESH) will be considered for funding. For information on the types of clinical trial that are within scope of this funding opportunity announcement, refer to Funding Opportunity Description, below. Funding Opportunity Number: PA-25-150. Assistance Listing: 93.242,93.853. Funding Instrument: G. Category: HL.

The NIH Exploratory/Developmental Grant supports exploratory and developmental research projects by providing support for the early and conceptual stages of these projects. These studies may involve considerable risk but may lead to a breakthrough in a particular area, or to the development of novel techniques, agents, methodologies, models, or applications that could have a major impact on a field of biomedical, behavioral, or clinical research. This Parent Notice of Funding Opportunity is for basic science experimental studies involving humans, referred to in NOT-OD-18-212 as prospective basic science studies involving human participants. These studies fall within the NIH definition of a clinical trial and also meet the definition of basic research. Types of studies that should submit under this FOA include studies that prospectively assign human participants to conditions (i.e., experimentally manipulate independent variables) and that assess biomedical or behavioral outcomes in humans for the purpose of understanding the fundamental aspects of phenomena without specific application towards processes or products in mind. Studies conducted with specific applications toward processes or products in mind should submit under the appropriate Clinical Trials Required or Clinical Trial Optional FOA. The proposed project must be related to the programmatic interests of one or more of the participating NIH Institutes and Centers (ICs) based on their scientific missions Funding Opportunity Number: PA-25-307. Assistance Listing: 93.173,93.213,93.233,93.242,93.273,93.279,93.361,93.837,93.838,93.839,93.840,93.865,93.866,93.867. Funding Instrument: G. Category: ED,HL,ISS.

The purpose of this initiative is to advance the science and implementation of innovative multi-level health care research for older adults from populations that experience health disparities. The initiative will support research designed to (1) gain a better understanding of appropriate screening, diagnostic, and clinical care guidelines in a primary care setting, (2) explore shared decision-making that is needed to enhance care planning and patient agency between clinicians and care teams with the older adult and their caregiver(s), and (3) identify effective strategies for care coordination. Funding Opportunity Number: PAR-24-273. Assistance Listing: 93.307,93.361,93.393,93.866. Funding Instrument: G. Category: ED,HL.

Rapid advances in genotyping and next generation sequencing technologies have led to the identification of genetic variants that are associated with a wide variety of congenital defects including human congenital anomalies (HCAs), intellectual developmental disabilities (IDDs) and inborn errors of metabolism (IEMs). Large quantities of genomic data collected from pediatric congenital anomalies cohorts are available to the research community through several databases such as the Database of Genotypes and Phenotypes (dbGaP), the Gabriella Miller Kids First Data Resource Portal, the European Genome-Phenome Archive and Clinical Genome Resource (ClinGen). The purpose of this initiative is to promote the screening, functional validation and characterization of congenital anomaly-associated genetic variants identified through public facing databases and individual efforts using in-silico tools, appropriate animal models, in vitro systems or multi-pronged approaches. This initiative addresses a challenging gap between identifying sequence variations of potential interest and recognizing which of those variations have functional effects on the phenotype of interest. Funding Opportunity Number: PAR-25-185. Assistance Listing: 93.121,93.351,93.865. Funding Instrument: G. Category: HL,ISS.

NIMH seeks applications for pilot effectiveness projects to evaluate the preliminary effectiveness of therapeutic and service delivery interventions for the post-acute management of mental health conditions that are matched to the stage of illness in terms of both their focus (e.g., consolidating and maintaining gains from initial treatment, managing residual symptoms/impairment, preventing relapse, promoting adherence and appropriate service use) and intensity/burden. In this pilot phase of effectiveness research, the trial should be designed to evaluate the feasibility, tolerability, acceptability, safety, and potential effectiveness of the approach; to address whether the intervention engages the target(s)/mechanisms(s) that is/are presumed to underlie the intervention effects; and to obtain preliminary data needed as a pre-requisite to a larger-scale effectiveness trial (e.g., comparative effectiveness study, practical trial) designed to definitely test the effectiveness of interventions to improve post-acute outcomes. This Notice of Funding Opportunity (NOFO) supports pilot effectiveness research to evaluate the feasibility, tolerability, acceptability, safety and preliminary indications of effectiveness of post-acute phase intervention approaches and inform the design of definitive effectiveness trials. Support for fully-powered, definitive effectiveness studies focused on post-acute phase interventions is provided via the R01 currently TEMP-24813. Funding Opportunity Number: PAR-25-206. Assistance Listing: 93.242. Funding Instrument: G. Category: HL.

The purpose of this NOFO is to build research about the effectiveness, implementation, and optimization of family navigation ED diversion models for non-urgent mental health problems. Models of interest are designed to (a) utilize triage tools to identify mental health acuity, (b) facilitate engagement in mental health services and needed resources, and (c) provide support, knowledge about the mental health condition, and facilitate linkages/address barriers to help-seeking among families. Funding Opportunity Number: PAR-25-289. Assistance Listing: 93.242. Funding Instrument: G. Category: HL.

The purpose of this NOFO is to build research about the effectiveness, implementation, and optimization of family navigation ED diversion models for non-urgent mental health problems. Models of interest are designed to (a) utilize triage tools to identify mental health acuity, (b) facilitate engagement in mental health services and needed resources, and (c) provide support, knowledge about the mental health condition, and facilitate linkages/address barriers to help-seeking among families. Funding Opportunity Number: PAR-25-288. Assistance Listing: 93.242. Funding Instrument: G. Category: HL.

The purpose of this Notice of Funding Opportunity (NOFO) is to solicit applications for exploratory and early-stage projects that focus on undruggable target classes within intractable human disease. Applicants will identify a human disease relevant undruggable target class and develop a method or agent that is selective for one or more targets within that target class. This NOFO is intended to jumpstart research that demonstrates innovative strategies to modulate targets that cannot be addressed by established therapeutic types, furthering the development of methods and/or agents selective for undruggable target classes. Funding Opportunity Number: PAR-25-442. Assistance Listing: 93.121,93.242,93.350,93.855,93.865,93.867. Funding Instrument: G. Category: HL.

The purpose of this initiative is to support the development of innovative research centers to foster nursing-led programs that promote community-partnered research to address persistent health challenges. Center applications developed in response to this RFA should propose strategies to strengthen the research infrastructure by establishing or expanding centralized research resources in School or College of Nursing (SON/CON), developing and enhancing nurse-led interdisciplinary teams, and building expertise in community-partnered research through conducting pilot research that applies NINR's research lenses. Center strategies should be informed by NINRs mission and should meaningfully engage the community throughout all activities. Funding Opportunity Number: PAR-25-439. Assistance Listing: 93.361. Funding Instrument: G. Category: ED,HL. Award Amount: Up to $500K per award.

This Notice of Funding Opportunity (NOFO) invites applications that propose to use mouse models to conduct rigorous preclinical testing of drugs or drug combinations currently used for other conditions, as well as investigational drugs at various stages of clinical development, predicted to be efficacious in AD/ADRD. This initiative will also support preclinical testing of repurposable or investigational drug candidates in combination with non-pharmacologic interventions leading to robust translational outcomes. The central goal is to establish robust proof of concept that will enable rational drug repurposing and combination therapy development for the treatment and prevention of AD/ADRD. Funding Opportunity Number: PAR-25-374. Assistance Listing: 93.866. Funding Instrument: G. Category: HL. Award Amount: Up to $1M per award.

The purpose of this funding announcement is to invite proposals focused on developing strategies and interventions to improve diagnostic safety in the heterogenous ambulatory care environment. AHRQ is interested in providing support designed to develop, test, and evaluate ambulatory care activities that will improve diagnostic safety and quality. Funding Opportunity Number: PA-23-290. Assistance Listing: 93.226. Funding Instrument: G. Category: HL. Award Amount: Up to $500K per award.

The National Center for Complementary and Integrative Health (NCCIH) announces this Notice of Funding Opportunity (NOFO) to solicit applications for research on how mind and body interventions through psychological and/or physical inputs (e.g., mindfulness meditation, yoga, acupuncture, massage, and other brain and/or body based interventions) impact mechanisms of emotional well-being (EWB) and their associations with whole person health (WPH), consistent with the NIH priority to address the health needs of the American people and improve their well-being. The NOFO will support rigorous and well-powered mechanistic research studies that are supported by strong preliminary data. The studies should examine the effects of mind and body interventions on innovative mechanisms of EWB (as the primary outcome), as well as the associated relationship with the Whole Person Health Index (WPHI, as a secondary outcome). To enhance research safety, rigor, and efficiency of NIH-funded mechanistic clinical trials, this initiative will use a two-phased award funding mechanism (R61/R33). The funding will support an initial phase (R61) to establish feasibility benchmarks for the proposed mechanistic clinical trial(s), followed by a second phase (R33) to complete the full-scale trials, which will be contingent upon successful completion of R61 milestones. Applications should provide preliminary data that are comparable in quality and quantity to those expected for an R01 proposal. Funding Opportunity Number: PAR-25-449. Assistance Listing: 93.213. Funding Instrument: G. Category: HL.

The National Cancer Institute (NCI) Method to Extend Research in Time (MERIT) (R37) Award provides extended grant support to Early Stage Investigators (ESIs). By providing such an opportunity for longer term support to ESIs, the NCI intends to offer flexibility and opportunity for creativity and innovation and additional time to successfully launch their careers and to become more established before having to submit renewal applications (NOT-CA-18-037). The objective of the NCI's ESI MERIT Award is to allow eligible investigators the opportunity to obtain up to 7 years of support in two segments: Funding Opportunity Number: PAR-25-324. Assistance Listing: 93.393,93.394,93.395,93.396,93.397,93.399. Funding Instrument: G. Category: ED,HL.

The purpose of this Notice of Funding Opportunity (NOFO) is to advance system-level approaches to improve patient safety by improving healthcare worker safety and well-being. Patient safety cannot be fully achieved without healthcare worker safety and well-being. This NOFO will contribute to AHRQs goal of reinvigorating the patient safety movement by adding fresh perspectives and insights of healthcare professionals to efforts to improve patient safety. Funding Opportunity Number: PA-24-093. Assistance Listing: 93.226. Funding Instrument: G. Category: HL. Award Amount: Up to $500K per award.

The purpose of this Notice of Funding Opportunity (NOFO) is to build evidence about the characteristics and value of primary care that influence patient outcomes and advance health equity, such as care coordination, continuity of care, and comprehensiveness of care, person-centered, whole healthcare, and trust, and how these can be improved and effectively delivered to strengthen primary healthcare. Funding Opportunity Number: PA-24-205. Assistance Listing: 93.226. Funding Instrument: G. Category: HL. Award Amount: Up to $500K per award.

EmPOWER Grant Program (2024-2025) is sponsored by Hawaii Energy. This program assists local nonprofits, small businesses, and restaurants in Hawaii with energy efficiency improvements and cost savings. Grants can cover up to 100% of project costs for eligible equipment such as air conditioners, HVAC system upgrades, solar water heaters, commercial kitchen equipment, and window films/tinting. Installation-related costs are also covered.

Hawaii Coral Reef Strategy Implementation Grants is a grant from the State of Hawaii Department of Land and Natural Resources, Division of Aquatic Resources, that funds coral reef conservation, monitoring, and restoration initiatives across Hawaii. The program supports projects aligned with NOAA's resilience-based management approach, addressing threats such as land-based pollution, coral disease and bleaching, invasive species, and changing ocean conditions. Eligible applicants include nonprofits, universities, and local government entities based in Hawaii. Awards range from $10,000 to $100,000. Applicants are encouraged to incorporate innovative approaches, including underwater technology and community monitoring efforts, to advance coral reef stewardship.

Harry and Jeanette Weinberg Foundation - Education & Early Child Care is a grant from The Harry and Jeanette Weinberg Foundation offering between ,000 and ,000 to nonprofits focused on education, early childhood care, aging, housing, health, jobs, and community services. The Foundation prioritizes organizations serving vulnerable populations in its six signature communities: Baltimore, Chicago, Hawaii, Israel, New York City, Northeastern Pennsylvania, and San Francisco. Education and early child care grants have supported college access programs, afterschool and summer academic programming, youth mentorship, and early childhood facility construction. Grants range from small operating support awards to major capital investments, and the Foundation serves both Jewish and general community organizations.

FY 2025 Ruth D. Gates Coral Reef Conservation Program - Supporting Hawaii's Sustainable Coral Reef Fisheries Management Plans is sponsored by NOAA Coral Reef Conservation Program. Technical support for developing Sustainable Coral Reef Fisheries Management Plans across Hawaiian Islands. Could support monitoring and scientific research to inform management, though primary focus is fisheries rather than drone technology.

Native Hawaiian Education is sponsored by Department of Education.

Native Arts + Cultures Foundation - LIFT Program is a grant from the Native Arts + Cultures Foundation providing $15,000 one-year awards to early-career Native artists working across traditional, visual, literary, performance, film, and interdisciplinary arts. Each award includes at least $5,000 for the artist's personal compensation and well-being, with remaining funds for project expenses. The LIFT program also provides professional development training in areas such as intellectual property, financial literacy, and grant writing; optional mentorship; and advocacy support. Eligibility is limited to enrolled members of US federally or state-recognized tribes or Alaska Native corporations, or persons of Native Hawaiian ancestry, who are emerging artists with fewer than ten years of experience and have not previously received a single award of $15,000 or more.

Hawaiʻi Resilience Fund is sponsored by Hawaii Community Foundation. Initially created to address the COVID-19 pandemic, this fund now provides rapid-response support for systemic resilience and disaster preparedness across the state of Hawaii. It focuses on filling gaps in government assistance and supporting vulnerable populations.

WaterSMART Program: Water Conservation Field Services Program (WCFSP) is sponsored by Department of the Interior, Bureau of Reclamation. The WCFSP encourages beneficiaries of Federal water projects to conserve water and assists agricultural and urban water districts in preparing and implementing water conservation plans.

Bank of Hawaii Foundation Program Grants is sponsored by Bank of Hawaii Foundation. Bank of Hawaii Foundation focuses on community development, human services, education, arts & culture, and other critical community needs, with a particular focus on programs and projects that provide significant impact within low and moderate income communities.

Native American and Native Hawaiian Library Services is sponsored by THE INSTITUTE OF MUSEUM AND LIBRARY SERVICES. The Native American and Native Hawaiian Library Services programs (NANH-L) are designed to assist Native American tribes and Native Hawaiians in improving core library services for their communities. NANH-L Basic Grants has one program goal and four objectives. Program Goal: Improve library and archival services for accessing learning. and preserving information with the community. Objective 1: Support the acquisition of library-related materials. Objective 2: Support programming for identified community priorities. Objective 3: Support training for library staff. Objective 4: Support project activities that include aspects of two or more of the objectives listed above. NANH-L Enhancement Grants has one goal with four associated objectives. Program Goal: Develop, enhance, or disseminate practices, programs, models, tools, or library staff training to strengthen library and archival services for Native American Tribes. Objective 1: Serve the learning needs and interests of the community. Objective 2: Improve community well-being. Objective 3: Provide access to and preservation of information and collections. Objective 4: Provide services to affected communities in the event of an emergency or disaster. The Native Hawaiian Library Services Grant program has one goal with four associated objectives. Program Goal: Develop, enhance, or disseminate practices, programs, models, tools, or staff training to strengthen library and archival services with Kānaka Maoli. Objective 1: Serve the learning needs and interests of the community. Objective 2: Improve Kānaka Maoli well-being. Objective 3: Provide access to and preservation of information and collections. Objective 4: Provide services to affected communities in the event of an emergency or disaster. This listing is currently active. Program number: 45.311. Last updated on 2024-11-26.

Coral Reef and Natural Resources (CRNR) Initiative is sponsored by U.S. Department of Interior (DOI). The Coral Reef and Natural Resources Initiative provides grant funding for management and protection of coral reefs and combating invasive species in U. S. jurisdictions.

Foster Youth Enhancement Grants is sponsored by Victoria S. and Bradley L. Geist Foundation. This program, administered via the Hawaii Community Foundation, provides grants for the enhancement of the lives of children and youth in the Hawaii foster care system.

Coral Emergency Response Fund is sponsored by NOAA Coral Reef Conservation Program via National Fish and Wildlife Foundation. Provides emergency non‑competitive assistance to U. S. jurisdictions and coral stewardship partnerships to respond to urgent harm to coral reefs or ecosystems.

Micro-Grants for Food Security Program (MGFSP) is sponsored by USDA AMS. MGFSP assists agricultural agencies or departments in eligible states and territories to increase the quantity and quality of locally grown food in food-insecure communities through small-scale gardening, herding, and livestock operations.

Strategic Priority Grants is sponsored by Harold K L Castle Foundation. Funding for projects aligned with the foundation's core strategic areas: Public Education Redesign and Enhancement, Nearshore Marine Resource Conservation, Climate Resiliency, and Strengthening Windward Oʻahu Communities. Applicants must begin with an Online Inquiry Form, and first-time applicants are required to call the foundation to discuss their project before submitting. Geographic focus: Hawaii (with priority on Windward Oʻahu) Focus areas: Public Education, Environmental Conservation, Climate Resiliency, Community Development

Rural Healthcare Program is sponsored by The Leona M. and Harry B. Helmsley Charitable Trust. Helmsley’s Rural Healthcare Program invests in technology solutions like telehealth to expand access to specialty care.

First Hawaiian Bank Foundation Grants is sponsored by First Hawaiian Bank Foundation. Supports nonprofit organizations that improve access to healthcare, build healthier communities, and meet human services needs across the Hawaiian Islands.

Folk and Traditional Arts: Apprentice Mentoring is sponsored by Hawaii State Foundation on Culture and the Arts. <div class="elementor-element elementor-element-ade5f7c elementor-widget elementor-widget-text-editor" dat Category: Arts & Culture.

Reduce, Reuse, Recycling Education and Outreach Grants is sponsored by ENVIRONMENTAL PROTECTION AGENCY. The objective of the grant program is to improve the effectiveness of residential composting and recycling programs through public education and outreach. The most recent funding opportunity under the Recycling Education and Outreach grant program funded projects that: decrease wasted food from households; expand markets for and sales of compost; and inform the public about new or existing residential food waste composting programs; provide information about the materials that are accepted as part of a residential food waste composting program; and increase collection rates and decrease physical contamination in residential food waste composting programs. This listing is currently active. Program number: 66.921. Last updated on 2026-01-06.

Native Hawaiian and Alaka Native Culture and Arts Development is sponsored by Department of the Interior. The Native Hawaiian and Alaka Native culture and arts development program promotes the scholarly study of, and instruction in, Native Hawaiian or Alaska Native arts and culture; establishes programs which culminate in the awarding of degrees in the various fields of Native Hawaiin or Alaska Native art and culture; and establishes centers and programs with respect to Native Hawaiian or Alaska Native art and culture. This listing is currently active. Program number: 15.071. Last updated on 2025-09-03.

Native Hawaiian Climate Resilience Program is sponsored by Department of the Interior. The Kapapahuliau Grant Program, authorized by the Inflation Reduction Act (P.L. 117-169, Title VIII Sec. 80002), provides funding to Native Hawaiian Organizations to leverage traditional Native Hawaiian knowledge in enhancing response and resilience to adverse weather events and subsequent environmental impacts. The activities funded by this program aim to promote the self-sufficiency, self-determination, and self-reliance of the Native Hawaiian Community and their lands. Projects supported by the grant will address various issues such as drought, wildfires, invasive species, storm-related flooding, tidal inundation, and erosion mitigation, while also considering the associated economic impacts. This listing is currently active. Program number: 15.098. Last updated on 2025-06-27.

National Institute on Aging Research Projects is sponsored by Department of Health And Human Services. The Institute seeks to understand the nature of aging and the aging process, and diseases and conditions associated with growing older, in order to extend the healthy, active years of life. This listing is currently active. Program number: 93.AGR. Last updated on 2026-01-12.

School Nutrition Training Grants is sponsored by Department of Agriculture.

Native Hawaiian Health Care Systems is sponsored by Department of Health And Human Services.

National Family Caregiver Support, Title VI, Part C, Grants To Indian Tribes And Native Hawaiians is sponsored by Department of Health And Human Services. To assist Indian Tribal and Native Hawaiian Organizations in providing multifaceted systems of support services for: (1) Family caregivers; and (2) grandparents or older individuals who are relative caregivers. Services to be provided include: information to caregivers about available services; assistance to caregivers in gaining access to the services; individual counseling and caregiver training to assist the caregivers in making decisions and solving problems relating to their caregiving roles; respite care to enable caregivers to be temporarily relieved from their caregiving responsibilities; and supplemental services, on a limited basis, to complement the care provided by caregivers. This listing is currently active. Program number: 93.054. Last updated on 2026-01-21.

Sexual Assault Services Culturally Specific Program is sponsored by Department of Justice. To increase culturally specific intervention, advocacy, accompaniment, support services, and related assistance for adult, youth, and child victims of sexual assault; family and household members of such victims; and those collaterally affected by the victimization, except for the perpetrator of such victimization. This listing is currently active. Program number: 16.023. Last updated on 2024-11-25.

Family Violence Prevention and Services/Discretionary is sponsored by Department of Health And Human Services. The purpose of this program is to fund a wide range of discretionary activities for the purpose of: (1) providing resource information, training and technical assistance to improve the capacity of individuals, organizations, government entities, and communities to prevent family violence, domestic violence, and dating violence and to provide effective intervention services; (2) improving the design, delivery, and coordination of services to address family violence, domestic violence and dating violence; (3) gathering information on the incidence and prevalence of family violence, domestic violence and dating violence; and (4) increasing knowledge and understanding of the issues through research, demonstration, and evaluation projects. Specific sections in the Act authorize funding for such discretionary projects as a National Resource Center on Domestic Violence; a National Indian Resource Center Addressing Domestic Violence and Safety for Indian Women; Special Issue Resource Centers including Culturally-Specific Issue Resource Centers; State Resource Centers to Reduce Tribal Disparities; Specialized Services for Abused Parents and Their Children; and a National Domestic Violence Hotline. This listing is currently active. Program number: 93.592. Last updated on 2026-01-15.

Community Arts Grants is sponsored by State Foundation on Culture and the Arts (Hawaii). Hawaii state program (formerly Biennium Grants) supporting nonprofit arts and culture organizations throughout the state.

Outreach Initiative Program is sponsored by Hawaii State Foundation on Culture and the Arts. FY2027 (time of performance: July 1, 2026 - June 30, 2027) nonprofit 501(c)3 arts and culture organizations March 1, 2026 - April 14, 2026 in HIePro America250 grant for Hawaiʻi veterans nonprofit 501 Category: Arts & Culture.

Nearshore Marine Resource Conservation Grants is sponsored by Harold K.L. Castle Foundation. This opportunity supports mission-aligned projects and measurable outcomes.

NOAA Coral Reef Conservation Program - Domestic Coral Reef Conservation Grants is sponsored by National Oceanic and Atmospheric Administration (NOAA). NOAA's Coral Reef Conservation Program (CRCP) publishes Federal Funding Opportunities in the Federal Register to solicit proposals for coral reef conservation activities, authorized by the Coral Reef Conservation Act of 2000.

FY26 Hawaii Coral Reef Assessment and Restoration Program is sponsored by State of Hawaii Division of Aquatic Resources. State grants for coral reef restoration projects involving marine biology research, propagation, and community monitoring in Hawaiian waters.

SFCA Culture Fellowships is sponsored by Hawaii State Foundation on Culture and the Arts. The State Foundation on the Culture and the Arts (SFCA) Culture Fellowship utilizes American Rescue Pla Category: Arts & Culture.

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Community Arts Grant Program is sponsored by Hawaii State Foundation on Culture and the Arts. Community Arts Grant Program 2028 nonprofit 501(c)3 arts and culture organizations Intent to Apply opens August 1, 2026 Category: Community Development.

Community Arts Grant Program is sponsored by Hawaii State Foundation on Culture and the Arts. Community Arts Grant Program 2028 nonprofit 501(c)3 arts and culture organizations Intent to Apply opens August 1, 2026 Category: Community Development.

Substance Use Prevention, Treatment, and Recovery Services Block Grant (SUBG) is sponsored by Substance Abuse and Mental Health Services Administration (SAMHSA). Allocates funds to states, including Hawaii, for substance use prevention, treatment, and recovery services.

Coastal Wetlands Planning, Protection and Restoration is sponsored by Department of the Interior. To provide competitive matching grants to coastal States for coastal wetlands conservation projects. The Coastal Wetlands Planning, Protection, and Restoration Act (Section 305, Title III, Public Law 101-646 U.S.C. 3954) established the National Coastal Wetlands Conservation Grant Program to acquire, restore, and enhance wetlands in coastal States. This listing is currently active. Program number: 15.614. Last updated on 2025-08-21.

Community Arts Grants is sponsored by Hawaii State Foundation on Culture and the Arts. Funding for organizations supporting programs and projects that advance the arts, culture, and the huma Category: Community Development.

Rural and Tribal Assistance Pilot Program is sponsored by Department of Transportation. The intent of this Program is to advance transportation infrastructure projects in rural and tribal communities by supporting development-phase activities for projects reasonably expected to be eligible for certain DOT credit and grant programs. Grants fund financial, technical, and legal assistance to states and rural and tribal communities. The grants are intended to augment organizational capacity in communities that may not have resources available to evaluate and develop projects that qualify for federal funding and financing programs. This listing is currently active. Program number: 20.943. Last updated on 2026-01-16.

State Digital Equity Planning and Capacity Grant is sponsored by Department of Commerce. The purpose of the State Digital Equity Planning and Capacity Grant Programs is to promote the achievement of digital equity, support digital inclusion activities, and build capacity for efforts by States relating to the adoption of broadband by residents of those States. States interested in participating in the State Digital Equity Capacity Grant Program must first complete State Digital Equity Plans as contemplated in Section 60304(c) of the Infrastructure Investment and Jobs Act of 2021, Public Law 117-58, 135 Stat. 429 (November 15, 2021) (Infrastructure Act or Act), also commonly known as the Bipartisan Infrastructure Law. The State Planning Grant Program funds may be used to 1) develop the State Digital Equity Plan of the State, and 2) to make subgrants to community, local, and tribal entities to assist in the development of the State Digital Equity Plan of the State. Digital Equity is fundamentally concerned with promoting full participation in the digital economy and society by all. Achievement of Digital Equity requires strategic investments in human and community capacity. Each State Digital Equity Plan prepared using State Digital Equity Planning Grant funding should include a clear description of the State’s vision for digital equity in the context of its overarching strategy and goals. This listing is currently active. Program number: 11.032. Last updated on 2026-01-26.

EPA Region 9 Pacific Southwest PFAS Tribal Drinking Water Sampling Project is sponsored by U.S. Environmental Protection Agency (Region 9). This opportunity supports mission-aligned projects and measurable outcomes.

Native Hawaiian Career and Technical Education is sponsored by Department of Education. To make grants to community-based organizations primarily serving and representing Native Hawaiians for programs or portions of programs authorized by, and consistent with, the Carl D. Perkins Career and Technical Education Act of 2006, as amended by the Strengthening Career and Technical Education for the 21st Century (Perkins V). This listing is currently active. Program number: 84.259. Last updated on 2024-11-13.

WaterSMART Drought Response Program is sponsored by Department of the Interior.

American Battlefield Protection is sponsored by Department of the Interior. To provide Federal financial assistance to State, local and tribal governments, other public entities, educational institutions, and private nonprofit organizations to identify, evaluate, interpret, and protect historic battlefields and sites associated with armed conflicts on American soil through non-acquisition projects and activities. This listing is currently active. Program number: 15.926. Last updated on 2025-09-03.

The Rosendin Foundation Grants is sponsored by The Rosendin Foundation. The Rosendin Foundation provides financial grants to community-focused 501(c)(3) non-profit organizations operating in states where Rosendin and MPS conduct business, including Hawaii. The foundation's grantmaking focuses on emotional, occupational, and nutritional health. They offer an annual financial grant cycle and emergency grant requests for unforeseen expenditures.

Augustus F. Hawkins Centers of Excellence—Teacher Preparation and Development is sponsored by Department of Education. This program focuses on the various aspects of the teacher preparation pipeline, including the recruitment, preparation, support, placement, and retention of teachers for and in high-need local education agencies (LEAs) to support underserved students. This listing is currently active. Program number: 84.428. Last updated on 2024-10-21.

Kūpuna Aging in Place Program is sponsored by Hawaii Community Foundation. This program supports organizations that provide a range of supportive services including community-based support services, adult day care & adult day health, and care partner support services for low- to moderate-income kūpuna (older adults) age 65 and older and their care part…

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The Community Reinvestment Program (CRP) is a grant from the Washington State Department of Commerce that funds community-designed initiatives to create lasting economic benefits and build wealth in underserved communities across Washington State. The program received million for the 2025-2027 biennium, including million in new funds. CRP supports economic development, reentry services, legal assistance, violence prevention, homeownership, workforce training, and small business creation. Priority is given to by-and-for organizations serving Black, Latine, Native American, Asian, Native Hawaiian, and Pacific Islander communities, though other organizations, lenders, and tribes are also eligible. Applications are accepted on a rolling basis.

Hawaiʻi State Poet Laureate 2026-2029 is sponsored by Hawaii State Foundation on Culture and the Arts. To promote and encourage appreciation of poetry and literary life in Hawaiʻi and the poetry community Category: Community Development.

Hawaii Community Foundation – Hawaii Youth Opportunities Initiative is sponsored by Hawaii Community Foundation. Supports Hawaii nonprofit or government organizations providing transition services (housing, employment, education, permanence) to foster youth ages 14–24, aligned with Jim Casey Youth Opportunities Initiative.