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"NIH Director's Transformative Research Award" is currently closed and not accepting applications.
NIH Director's Transformative Research Award is sponsored by NIH Common Fund. Supports individuals or teams proposing transformative projects that are inherently risky but have the potential to create or overturn fundamental paradigms.
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NIH Director's Transformative Research Award | NIH Common Fund NIH Director's Transformative Research Award NIH Director's Transformative Research Award FY2026 NIH Director’s Transformative Research Award informational video Part of the High-Risk, High-Reward Research program, the NIH Director's Transformative Research Award supports individuals or teams proposing transformative projects that are inherently risky and untested but have the potential to create or overturn fundamental paradigms and may require very large budgets.
Part of the High-Risk, High-Reward Research program , the award supports individuals or teams proposing transformative projects that are inherently risky and untested but have the potential to create or overturn fundamental paradigms and may require very large budgets.
Open to all career stages Open to individuals or teams No preliminary data required Research effort commensurate to project needs No prior approval required for large budget requests See the Award Overview for more information.
Application & Award Guide Recent News & Announcements Scientists Discover Possible Anti-Aging Treatment in Mouse Cells A Genetic Checkpoint that Could put Alzheimer’s Disease to REST NIH to award over $207 million to support highly innovative biomedical and behavioral research projects This page last reviewed on
According to the current listing, eligibility includes: Open to all career stages, individuals or teams. Confirm the full requirements in the official notice before applying.
The published deadline was September 3, 2026, which has passed. Check the official notice for any future application windows before investing time in a proposal.
NIH Director's Transformative Research Award is funded by NIH Common Fund. Verify program details on the funder's official page before applying.
Yes — this listing is flagged as national in scope, so applicants across the U.S. may apply, subject to the sponsor's other eligibility criteria.
Applications go through the funder's official portal — the Apply Now link on this page goes there directly.
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