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Find similar grantsNIH Exploratory/Developmental Research Grant Award (R21 Clinical Trial Optional) is sponsored by NIH NIMH. Supports exploratory and developmental research projects in areas such as mental health, including optional clinical trials.
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NIH Websites Are Changing Opportunities & Announcements Funding Strategy for Grants Grant Writing & Approval Process Non-Clinical trial R21 applications NIMH accepts non-clinical trial R21 applications under the following opportunities: PA-25-304: NIH Exploratory/Developmental Research Grant Program (Parent R21 Clinical Trial Not Allowed) PA-25-150: Joint NINDS/NIMH Exploratory Neuroscience Research Grant (R21 Clinical Trial Not Allowed) Applications must support exploratory and foundational research projects aligned with the NIMH scientific mission .
Clinical trial R21 applications NIMH accepts mechanistic clinical trial R21 applications under the following opportunities: PA-25-306: NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Required) PA-25-307: NIH Exploratory/Developmental Research Project Grant (Parent R21 Basic Experimental Studies with Humans Required) See the Consolidated Notice on NIMH Clinical Trials Policies (NOT-MH-23-375 ), for a summary of NIMH’s polices on support for mechanistic and other clinical trials.
Potential applicants are strongly encouraged to contact the Agency Contacts listed in the targeted funding opportunity before applying. NIMH Extramural Research Programs: Review to understand the broad range of scientific fields supported by NIMH.
According to the current listing, eligibility includes: Individuals with a doctoral degree and a demonstrated record of research excellence. Confirm the full requirements in the official notice before applying.
The current listing shows $275,000 over 2 years. Verify award ceilings, matching requirements, and allowable costs in the official notice.
NIH Exploratory/Developmental Research Grant Award (R21 Clinical Trial Optional) is funded by NIH NIMH. Verify program details on the funder's official page before applying.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
PA-27-037 consolidates the Predoctoral to Postdoctoral Transition Award into a single parent announcement across 20 NIH components, with the next deadline December 8, 2026. The eligibility gate is not the science — it is a mandatory change of institution and mentor between the F99 and K00 phases.
Read articleA draft executive order would have put OMB Director Russell Vought on a commission with final say over NIH awards after peer review. Sen. Collins killed it by pointing at a provision Congress already passed. Here is what the episode teaches applicants about the December 11 cliff.
Read articlePA-27-034, PA-27-035 and PA-27-036 replace the institute-specific R25 announcements that research education programs have been built around for a decade. NCI, NIDA and NIGMS have already expired theirs early. Here is what the consolidation actually changes: an 8% indirect cost ceiling, a US-citizens-and-permanent-residents participant rule, a cooperative agreement variant that only exists on one of the three, and no clinical-trial-allowed companion anywhere.
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