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Research Infrastructure Programs - Research Projects is sponsored by Department of Health And Human Services. The Office of Research Infrastructure Programs (ORIP), within the Division of Program Coordination, Planning, and Strategic Initiatives (DPCPSI) in the NIH Office of the Director, supports extramural biomedical research by strengthening the infrastructure that enables scientific discovery.
ORIP advances human health by fostering the development of critical research models, biomaterials, and technologies; expanding access to state-of-the-art instrumentation and facilities; supporting education and training programs; and assisting small businesses in translating innovative technologies.
Through its two divisions, the Division of Comparative Medicine (DCM) and the Division of Construction and Instruments (DCI), ORIP plays a critical role in accelerating biomedical research nationwide.
DCM develops and sustains essential research models and biological resources, manages the infrastructure required for their use and distribution, and provides training to ensure investigators have reliable access to high-quality models and facilities.
DCI supports shared, cost-effective access to advanced scientific instrumentation, modernizing research facilities, and providing critical equipment that enables transformative biomedical discoveries. Together, DCM and DCI strengthen U.S. competitiveness and ensure the biomedical research community has the infrastructure necessary to address emerging health challenges, prevent disease, promote health, and advance foundational science.
This listing is currently active. Program number: 93. 3RP.
Last updated on 2026-01-28.
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Or search similar grants →According to the current listing, eligibility includes: Institutions of higher education, hospitals, and other institutions and organizations, both nonprofit and for-profit, seeking to establish, continue, or enlarge programs consistent with the objectives of the program. To be eligible for instrumentation and equipment programs, applications must be Private nonprofit institutions/organizations, Public nonprofit institutions/organizations. Eligible applicant types include: For-Profit Organization, Nonprofit Organization, Small Business Person, County Government (inclusive of boroughs in Alaska, parishes and other governmental entities with geographic regional control and authority), Federally Recognized Indian/Native American/Alaska Native Tribal Government, Municipality or Township government (inclusive of cities, towns, boroughs (except in Alaska), and villages), U.S. State Government (including the District of Columbia). Confirm the full requirements in the official notice before applying.
The current listing shows recent federal obligations suggest $12,442,852 (2026). Verify award ceilings, matching requirements, and allowable costs in the official notice.
Research Infrastructure Programs - Research Projects accepts applications on a rolling basis — there is no single fixed deadline. Check the official notice for any cycle-specific review dates.
Yes — Research Infrastructure Programs - Research Projects is offered by Department of Health And Human Services and this listing comes from SAM.gov, an official U.S. federal source. Federal applications generally require registrations (for example SAM.gov or an agency submission portal), so allow extra lead time.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
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Research Infrastructure Programs - Construction is sponsored by Department of Health And Human Services. The Office of Research Infrastructure Programs (ORIP), within the Division of Program Coordination, Planning, and Strategic Initiatives (DPCPSI) in the NIH Office of the Director, supports extramural biomedical research by strengthening the infrastructure that enables scientific discovery. ORIP advances human health by fostering the development of critical research models, biomaterials, and technologies; expanding access to state-of-the-art instrumentation and facilities; supporting education and training programs; and assisting small businesses in translating innovative technologies. Through its two divisions, the Division of Comparative Medicine (DCM) and the Division of Construction and Instruments (DCI), ORIP plays a critical role in accelerating biomedical research nationwide. DCM develops and sustains essential research models and biological resources, manages the infrastructure required for their use and distribution, and provides training to ensure investigators have reliable access to high-quality models and facilities. DCI supports shared, cost-effective access to advanced scientific instrumentation, modernizing research facilities, and providing critical equipment that enables transformative biomedical discoveries. Together, DCM and DCI strengthen U.S. competitiveness and ensure the biomedical research community has the infrastructure necessary to address emerging health challenges, prevent disease, promote health, and advance foundational science. This listing is currently active. Program number: 93.CN1. Last updated on 2026-01-28.
Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative is sponsored by Department of Health And Human Services. To provide extramural research support for the Brain Research Through Advancing Innovative Neurotechnologies® (BRAIN) Initiative’s aim of revolutionizing our understanding of the brain and its function in unprecedented detail. The NIH BRAIN Initiative’s focus is foundational development of new technologies and tools to map, monitor, and modulate brain circuits in model systems and humans – toward the ultimate goal of treating and curing human brain disorders. BRAIN Initiative research adheres to open, and ethical science. BRAIN-supported research areas include comprehensive cataloguing, mapping, accessing and characterization of brain cell types ; probing neural circuits that interact and produce behavior, cognition, and emotion; developing and employing new technologies to monitor function and connectivity of synapses, circuits, and whole brains; partnering with human research participants, including utilizing neurotechnologies in first-in-human clinical studies, to study the human brain in the context of brain injury and brain disorders; and establishing data-sharing platforms and computational models that help decode brain processes and functions. Within these scientific focus areas, the Initiative supports research project grants, cooperative agreements, workforce development awards and Small Business Innovation Research awards. Research supported by the Initiative has a strong commitment to broad dissemination of newly developed technologies, and to considering neuroethical issues related to studying the human brain and the neuroscience advances that follow from this research. New frontiers for BRAIN research will adhere to, and build on, what has been learned to date and adapt to the rapidly changing scientific landscape and neuroscience ecosystem. This listing is currently active. Program number: 93.BZ1. Last updated on 2026-01-28.
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