Shared Instrumentation Grant (SIG) Program

Research Infrastructure Programs - Research Centers is sponsored by Department of Health And Human Services. The Office of Research Infrastructure Programs (ORIP), within the Division of Program Coordination, Planning, and Strategic Initiatives (DPCPSI) in the NIH Office of the Director, supports extramural biomedical research by strengthening the infrastructure that enables scientific discovery. ORIP advances human health by fostering the development of critical research models, biomaterials, and technologies; expanding access to state-of-the-art instrumentation and facilities; supporting education and training programs; and assisting small businesses in translating innovative technologies. Through its two divisions, the Division of Comparative Medicine (DCM) and the Division of Construction and Instruments (DCI), ORIP plays a critical role in accelerating biomedical research nationwide. DCM develops and sustains essential research models and biological resources, manages the infrastructure required for their use and distribution, and provides training to ensure investigators have reliable access to high-quality models and facilities. DCI supports shared, cost-effective access to advanced scientific instrumentation, modernizing research facilities, and providing critical equipment that enables transformative biomedical discoveries. Together, DCM and DCI strengthen U.S. competitiveness and ensure the biomedical research community has the infrastructure necessary to address emerging health challenges, prevent disease, promote health, and advance foundational science. This listing is currently active. Program number: 93.3RC. Last updated on 2026-01-28.

The Rural Utilities Service (RUS or the Agency), a Rural Development (RD) Agency of the United States Department of Agriculture (USDA), is soliciting Letters of Interest (LOI) for loan Applications, announcing the Application process for those loans, and providing deadlines for Applications from eligible entities under the Powering Affordable Reliable Technology (PART) Energy Program. These loan funds will be made to qualified PART Applicants to finance power generation Projects for Renewable Energy Resource (RER) systems or Energy Storage Systems (ESS) that support RER Projects. The PART Program is making approximately $410 million in appropriated budget authority (BA) funding available under the Inflation Reduction Act of 2022 (IRA). RUS will process and evaluate complete LOI on a rolling basis in the order they are received. The PART Program is to be carried out by the RUS pursuant to Section 22001 of the IRA. Section 22001 of the IRA amends Section 9003 of the Farm Security and Rural Investment Act of 2002 by adding new subsection (h). Section 22001 of the IRA provides RUS with appropriated funds “for the cost of loans under Section 317 of the RE Act.” Additionally, Section 22001 of the IRA provides that PART funds may be utilized to finance Projects that store electricity generated from eligible energy sources listed under Section 317 of the RE Act. These Project Loans or System Loans will be forgiven up to forty percent (40%), provided the Awardee and the Project otherwise meet the terms and conditions of the loan forgiveness. Approximately $410 million in budget authority is being made available under this Notice. The Administrator reserves the right to increase this funding level should additional funds become available or reduce funding in the event an insufficient number of high-quality projects are submitted for consideration. Cost Sharing or Matching: (a) Project Loans. Awards will finance up to 75% of the total capitalized costs of a Project. Awardees will be required to provide at least 25% of the Project’s total capitalized cost in the form of cash or equity investments, which may not be derived from debt instruments. However, the Agency may utilize its authority under Section 306F of the RE Act and finance up to 100% of the costs of the Projects benefiting SUTA areas. (b) System Loans. PART System Loans may cover up to 100% of the total costs of the Project. Funding Opportunity Number: RUS-PART-2026. Assistance Listing: 10.757. Funding Instrument: O. Category: EN. Award Amount: $1M – $100M per award.

The U.S. Fish and Wildlife Service (Service) requests interested entities to submit research, restoration, and Regional Project proposals for the restoration of the Great Lakes Basin fish and wildlife resources, as authorized under the Great Lakes Fish and Wildlife Restoration Act (16U.S.C. 941c). The purpose of the Great Lakes Fish and Wildlife Restoration Act (GLFWRA) is to provide assistance to States, Indian Tribes, and other interested entities to encourage cooperative conservation, restoration, research, and management of the fish and wildlife resources and their habitats in the Great Lakes Basin. Supported in part by the Great Lakes Restoration Initiative, we expect approximately $3.5 million to support proposals this fiscal year. Available funding and proposal awards are subject to final Congressional appropriations for Fiscal Year 2026. Up to 33 and one-third percent of the total Congressional appropriation to the GLFWRA is eligible to fund Regional Project proposals. Expected award funding for Regional Project proposals is between $200,000 to $500,000. Successful restoration and research proposals have ranged from $2,000 to $500,000 with the average proposal at $217,843. Expected award funding for restoration and research proposals is between $10,000 and $250,000. Selected restoration and research proposals and Regional Project proposals will be awarded funding for the duration of the proposal via a grant or cooperative agreement between the recipient and the Service. Funding will be made available once the official award letter has been received by the successful applicant and the performance period has started. Continuation of proposals funded in previous fiscal years are eligible but will be considered and reviewed as a new proposal. Restoration and research proposals will be awarded a grant agreement and Regional Project proposals will be awarded a cooperative agreement under this announcement. Cooperative Ecosystem Studies Units (CESU) Network partners that submit Regional Project proposals that qualify as CESU proposals will be subject to the CESU indirect cost rate cap. Regional Projects are authorized activities of the Service related to fish and wildlife resource protection, restoration, maintenance, and enhancement impacting the resources of multiple States or Indian Tribes with fish and wildlife management authority in the Great Lakes Basin. The two-page restoration and research pre-proposals and Regional Project proposals are submitted to the Service to determine eligibility and the Proposal Review Committee (PRC) scores and ranks the proposals using GLFWRA Review Criteria (Review Criteria). Successful restoration and research pre-proposal applicants are invited to submit full proposals, which are scored and ranked by the PRC using the Review Criteria. The PRC recommends the restoration and research full proposals and Regional Project proposals for funding to the Service’s Midwest Region 3 Regional Director for approval. Successful restoration and research and Regional Project proposal applicants can anticipate receiving an official grant or cooperative agreement award letter between January and March 2027. Funding Opportunity Number: F26AS00062. Assistance Listing: 15.688. Funding Instrument: CA,G. Category: NR. Award Amount: $2K – $500K per award.