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Small Business Innovation Research and Small Business Technology Transfer Programs (SBIR/STTR) - DOE Office of Science is sponsored by U.S. Department of Energy (DOE), Office of Science. The DOE SBIR/STTR programs are competitive non-dilutive funding programs that fund eligible small businesses to engage in Federal Research/Research and Development (R/R&D) with the goal of product commercialization.
Projects must have the potential for commercialization and be responsive to DOE mission areas, including Energy Production & Use, Fundamental Energy Science, Defense Nuclear Nonproliferation, and Environmental Management.
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Or search similar grants →According to the current listing, eligibility includes: Eligible small businesses conducting R/R&D with commercialization potential that supports DOE mission areas. Only companies with a Phase I grant may respond to Phase II FOAs. Confirm the full requirements in the official notice before applying.
The current listing shows phase I: up to $200,000 over nine months; Phase II: up to $1,100,000 over two years. Verify award ceilings, matching requirements, and allowable costs in the official notice.
Small Business Innovation Research and Small Business Technology Transfer Programs (SBIR/STTR) - DOE Office of Science is funded by U.S. Department of Energy (DOE), Office of Science. Verify program details on the funder's official page before applying.
Yes — this listing is flagged as national in scope, so applicants across the U.S. may apply, subject to the sponsor's other eligibility criteria.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
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Continuations of Solicitation for the Office of Science Financial Assistance Program (DE-FOA-0003600) is sponsored by U.S. Department of Energy (DOE), Office of Science. This is an open solicitation from the DOE Office of Science that accepts proposals year-round in various research topic areas spanning the Office of Science program areas.
The FY 2026 Continuation of Solicitation for the Office of Science Financial Assistance Program is an open annual grant from the U.S. Department of Energy (DOE) Office of Science that funds research across its core program areas, including Advanced Scientific Computing Research, Basic Energy Sciences, Biological and Environmental Research, Fusion Energy Sciences, High Energy Physics, Nuclear Physics, and Isotope R&D and Production. Any research within SC's Congressionally authorized mission may be proposed under this solicitation, which remains open throughout the fiscal year. Eligible applicants include colleges and universities, non-profit and for-profit research organizations, DOE national laboratories, small businesses, and other federal research organizations. Anticipated awards range from $750,000 to $3,000,000 per year; the solicitation closes September 30, 2026.
The Trump administration committed $5B and 278 projects across 15+ agencies to the Genesis Mission. Here's the structure — and how to position for the next wave.
Read articleOn July 22, 2026, the White House announced more than $5 billion in federal commitments for the Genesis Mission — the Department of Energy-led national initiative to fuse AI, exascale computing, and the 17 national labs into a single scientific platform. Nearly 300 projects across all 50 states were selected from a historic Request for Applications, and 15-plus agencies are now attaching funding to a set of National Science and Technology Challenges. Here is what the Genesis Mission is, how the money is structured, and the concrete on-ramps for researchers, universities, and small businesses who were not in the first cohort.
Read articleDOE's FY2026 Office of Science open-call solicitation (DE-FOA-0003600) makes roughly $500 million available across about 500 awards of $50,000 to $5 million — across computing, physics, chemistry, biology, fusion, and isotopes — with a rolling window that stays open through September 30, 2026. Unlike a targeted NOFO, it lets investigators propose almost anything within the agency's mission. Here is how the open call actually works, why it is chronically underused, and how to write into it.
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