Strategies to promote sleep and reduce delirium in intensive care unit settings (PCORI-funded CER project)

Strategies to promote sleep and reduce delirium in intensive care unit settings (PCORI-funded CER project) is sponsored by Patient-Centered Outcomes Research Institute (PCORI). This PCORI-funded patient-centered comparative clinical effectiveness research (CER) project will examine the comparative effectiveness of different approaches to improving sleep and reducing delirium in ICU patients, comparing nondrug approaches versus those that combine nondru…

* PCORI's Research Funding Process * What You Need to Know to Apply ### Applicant and Awardee Resources * Research & Related Projects #### Research & Related Projects * CER Results On the Path to Impact * PCORI in the Literature #### Engagement in Research * Foundational Expectations for Partnerships in Research * Foundational Expectations for Partnerships * Background on the Foundational Expectations * Benefits of Engagement in Research * Real-World Examples by Foundational Expectation * Frequently Asked Questions * Why Patient Engagement in Research Matters * The Science of Engagement in Research * Tools and Resources To Support Engagement in Research * Engagement in Health Research Literature Explorer * Engagement Award Program * Get Involved: Participate in the Research Process * Implementation of Evidence #### Implementation of Evidence * Putting Evidence to Work * Evidence Synthesis Reports and Interactive Visualizations * Emerging Topics: Reports and Horizon Scans * Intellectual and Developmental Disabilities * Maternal Morbidity and Mortality * 2026 PCORI Annual Meeting * Financial Statements and Reports * Governing & Operations Documents * Monitoring and Evaluating Progress * Advisory Panel Openings * Application Review and Selection Process * Procurement Opportunities * PCORI's Research Funding Process * What You Need to Know to Apply * Research & Related Projects Toggle Menu * CER Results On the Path to Impact * PCORI in the Literature * Engagement in ResearchToggle Menu * Foundational Expectations for Partnerships in ResearchToggle Menu * Foundational Expectations for Partnerships * Background on the Foundational Expectations * Benefits of Engagement in Research * Real-World Examples by Foundational Expectation * Frequently Asked Questions * Why Patient Engagement in Research Matters * The Science of Engagement in Research * Tools and Resources To Support Engagement in Research * Engagement in Health Research Literature Explorer * Engagement Award Program * Get Involved: Participate in the Research Process * Implementation of Evidence Toggle Menu * Putting Evidence to Work * Evidence Synthesis Reports and Interactive Visualizations * Emerging Topics: Reports and Horizon Scans * Health TopicsToggle Menu * Intellectual and Developmental Disabilities * Maternal Morbidity and Mortality * News & Events Toggle Menu * 2026 PCORI Annual Meeting * Financial Statements and Reports * Governing & Operations Documents * Monitoring and Evaluating Progress * PCORI Advisory PanelsToggle Menu * Advisory Panel Openings * Application Review and Selection Process * Procurement Opportunities Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others.

_See the Portfolio User Guide_ * - [x] Show Only Projects With Results(710) Show Only Projects With Results(710) * - [x] Research(1038) Research(1038) * - [x] Research Conducted Using PCORnet®(85) Research Conducted Using PCORnet®(85) * - [x] Engagement in Research(1322) Engagement in Research(1322) * - [x] Engagement Award Project(667) Engagement Award Project(667) * - [x] Building Capacity for Small Organizations(18) Building Capacity for Small Organizations(18) * - [x] Dissemination(102) Dissemination(102) * - [x] Engagement Award Convening(288) Engagement Award Convening(288) * - [x] Convening: Dissemination(8) Convening: Dissemination(8) * - [x] Engagement Award Conference: Evidence Synthesis(14) Engagement Award Conference: Evidence Synthesis(14) * - [x] Pipeline to Proposal(353) Pipeline to Proposal(353) * - [x] Tier A(50) Tier A(50) * - [x] Tier I(123) Tier I(123) * - [x] Tier II(112) Tier II(112) * - [x] Tier III(68) Tier III(68) * - [x] Dissemination and Implementation(169) Dissemination and Implementation(169) * - [x] Implementation Project (Limited Competition D&I PFA)(44) Implementation Project (Limited Competition D&I PFA)(44) * - [x] Implementation Project (Implementation of Effective Shared Decision Making Approaches PFA)(10) Implementation Project (Implementation of Effective Shared Decision Making Approaches PFA)(10) * - [x] Implementation Project (Open Competition PFA: Implementation of Findings from PCORI’s Research Investments)(5) Implementation Project (Open Competition PFA: Implementation of Findings from PCORI’s Research Investments)(5) * - [x] Dissemination Project (Limited Competition D&I PFA)(3) Dissemination Project (Limited Competition D&I PFA)(3) * - [x] Health Systems Implementation Initiative (HSII)(99) Health Systems Implementation Initiative (HSII)(99) * - [x] Capacity Building Project (HSII)(41) Capacity Building Project (HSII)(41) * - [x] Implementation Project (HSII)(58) Implementation Project (HSII)(58) * - [x] Research Infrastructure(124) Research Infrastructure(124) * - [x] PCORnet® Coordinating Center Phase 4(3) PCORnet® Coordinating Center Phase 4(3) * - [x] PCORnet® Project(2) PCORnet® Project(2) * - [x] PCORnet®: Clinical Research Network (Phase 4)(8) PCORnet®: Clinical Research Network (Phase 4)(8) * - [x] PCORnet® Initiative on Health Plan/System Data Partnerships (A Stepwise Approach to Collaboration)(2) PCORnet® Initiative on Health Plan/System Data Partnerships (A Stepwise Approach to Collaboration)(2) * - [x] PCORnet®: Clinical Data Research Networks (CDRN) Phase I(11) PCORnet®: Clinical Data Research Networks (CDRN) Phase I(11) * - [x] PCORnet®: Clinical Data Research Networks (CDRN) Phase II(13) PCORnet®: Clinical Data Research Networks (CDRN) Phase II(13) * - [x] PCORnet®: Clinical Research Network (CRN) 2020(9) PCORnet®: Clinical Research Network (CRN) 2020(9) * - [x] PCORnet®: Clinical Research Network (Phase 3)(8) PCORnet®: Clinical Research Network (Phase 3)(8) * - [x] PCORnet®: Patient Powered Research Networks (PPRN) Phase I(19) PCORnet®: Patient Powered Research Networks (PPRN) Phase I(19) * - [x] PCORnet®: Patient Powered Research Networks (PPRN) Phase II(20) PCORnet®: Patient Powered Research Networks (PPRN) Phase II(20) * - [x] PCORnet® Coordinating Center Phase II(2) PCORnet® Coordinating Center Phase II(2) * - [x] PCORnet® Coordinating Center Phase 3(5) PCORnet® Coordinating Center Phase 3(5) * - [x] PPRN Limited Competition Award(8) PPRN Limited Competition Award(8) * - [x] Other Evidence Products(32) Other Evidence Products(32) ### Status More Information Project Status View definitions of the life cycle of an awarded project.

View the DefinitionsClose * - [x] Completed(2011) Completed(2011) * - [x] Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted(538) Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted(538) * - [x] Completed; PCORI Public and Professional Abstracts Posted(127) Completed; PCORI Public and Professional Abstracts Posted(127) * - [x] PCORI Peer Review(36) PCORI Peer Review(36) * - [x] PCORI Peer-Review Process Complete(13) PCORI Peer-Review Process Complete(13) * - [x] In PCORI Peer-Review Process(23) In PCORI Peer-Review Process(23) * - [x] Ongoing(513) Ongoing(513) * - [x] Awarded; In progress(171) Awarded; In progress(171) * - [x] In progress; Recruiting(123) In progress; Recruiting(123) * - [x] In progress; Enrollment complete(23) In progress; Enrollment complete(23) * - [x] In progress; Data collected(36) In progress; Data collected(36) * - [x] In progress; Recruitment not applicable(92) In progress; Recruitment not applicable(92) * - [x] In progress; Not yet recruiting(38) In progress; Not yet recruiting(38) * - [x] PCORnet: Phase I completed(2) PCORnet: Phase I completed(2) * - [x] PCORnet: Phase I completed; Phase II in progress(16) PCORnet: Phase I completed; Phase II in progress(16) * - [x] Other(125) Other(125) * - [x] Awarded; Contract pending(112) Awarded; Contract pending(112) * - [x] Awarded; Contract not executed(1) Awarded; Contract not executed(1) * - [x] Concluded after feasibility assessment(1) Concluded after feasibility assessment(1) * - [x] Terminated(11) Terminated(11) ### State More Information State The state where the project originates, or where the primary institution or organization is located.

View GlossaryClose * - [x] Alabama(22) Alabama(22) * - [x] Alaska(2) Alaska(2) * - [x] Arizona(28) Arizona(28) * - [x] Arkansas(28) Arkansas(28) * - [x] California(297) California(297) * - [x] Colorado(64) Colorado(64) * - [x] Connecticut(37) Connecticut(37) * - [x] Delaware(5) Delaware(5) * - [x] District of Columbia(129) District of Columbia(129) * - [x] Florida(85) Florida(85) * - [x] Georgia(53) Georgia(53) * - [x] Hawaii(4) Hawaii(4) * - [x] Idaho(6) Idaho(6) * - [x] Illinois(130) Illinois(130) * - [x] Indiana(20) Indiana(20) * - [x] Iowa(11) Iowa(11) * - [x] Kansas(31) Kansas(31) * - [x] Kentucky(14) Kentucky(14) * - [x] Louisiana(26) Louisiana(26) * - [x] Maine(12) Maine(12) * - [x] Maryland(155) Maryland(155) * - [x] Massachusetts(248) Massachusetts(248) * - [x] Michigan(80) Michigan(80) * - [x] Minnesota(38) Minnesota(38) * - [x] Mississippi(6) Mississippi(6) * - [x] Missouri(42) Missouri(42) * - [x] Montana(6) Montana(6) * - [x] Nebraska(6) Nebraska(6) * - [x] Nevada(5) Nevada(5) * - [x] New Hampshire(29) New Hampshire(29) * - [x] New Jersey(24) New Jersey(24) * - [x] New Mexico(35) New Mexico(35) * - [x] New York(153) New York(153) * - [x] North Carolina(125) North Carolina(125) * - [x] Ohio(77) Ohio(77) * - [x] Oklahoma(7) Oklahoma(7) * - [x] Oregon(35) Oregon(35) * - [x] Pennsylvania(208) Pennsylvania(208) * - [x] Puerto Rico(5) Puerto Rico(5) * - [x] Rhode Island(15) Rhode Island(15) * - [x] South Carolina(21) South Carolina(21) * - [x] Tennessee(42) Tennessee(42) * - [x] Texas(70) Texas(70) * - [x] Utah(37) Utah(37) * - [x] Vermont(5) Vermont(5) * - [x] Virginia(50) Virginia(50) * - [x] Washington(99) Washington(99) * - [x] West Virginia(7) West Virginia(7) * - [x] Wisconsin(33) Wisconsin(33) * - [x] Wyoming(6) Wyoming(6) ### Funding Opportunity Type * - [x] Addressing Disparities(98) Addressing Disparities(98) * - [x] Addressing Rare Diseases(4) Addressing Rare Diseases(4) * - [x] Addressing Substance Use(1) Addressing Substance Use(1) * - [x] Addressing Violence and Trauma(1) Addressing Violence and Trauma(1) * - [x] Advancing the Science of Engagement(28) Advancing the Science of Engagement(28) * - [x] Assessment of Prevention, Diagnosis, and Treatment Options(143) Assessment of Prevention, Diagnosis, and Treatment Options(143) * - [x] Asthma Treatment Options for African Americans and Hispanics/Latinos(8) Asthma Treatment Options for African Americans and Hispanics/Latinos(8) * - [x] Brief Interventions for Adolescent Alcohol Use(6) Brief Interventions for Adolescent Alcohol Use(6) * - [x] Broad Pragmatic Studies(68) Broad Pragmatic Studies(68) * - [x] Clinical Management of Hepatitis C Infection(2) Clinical Management of Hepatitis C Infection(2) * - [x] Clinical Strategies for Managing and Reducing Long-Term Opioid Use for Chronic Pain(4) Clinical Strategies for Managing and Reducing Long-Term Opioid Use for Chronic Pain(4) * - [x] Clinical Trial of a Multifactorial Fall Injury Prevention Strategy in Older Persons(1) Clinical Trial of a Multifactorial Fall Injury Prevention Strategy in Older Persons(1) * - [x] Communication and Dissemination Research(52) Communication and Dissemination Research(52) * - [x] Community-Based Palliative Care Delivery for Adult Patients with Advanced Illnesses and their Caregivers(7) Community-Based Palliative Care Delivery for Adult Patients with Advanced Illnesses and their Caregivers(7) * - [x] Comparative Effectiveness of Interventions Targeting Mental Health in Individuals with Intellectual and Developmental Disabilities(3) Comparative Effectiveness of Interventions Targeting Mental Health in Individuals with Intellectual and Developmental Disabilities(3) * - [x] Coordinating Center Functions to Advance Phase 3 of PCORnet(5) Coordinating Center Functions to Advance Phase 3 of PCORnet(5) * - [x] Coordinating Center Services to Advance Phase 4 of PCORnet(3) Coordinating Center Services to Advance Phase 4 of PCORnet(3) * - [x] COVID-19 Targeted PFA (2020)(9) COVID-19 Targeted PFA (2020)(9) * - [x] COVID-19-Related Project Enhancement(120) COVID-19-Related Project Enhancement(120) * - [x] Engagement Award Special Cycle: Supporting Engagement in and Dissemination of PCOR/CER in the Context of COVID-19(25) Engagement Award Special Cycle: Supporting Engagement in and Dissemination of PCOR/CER in the Context of COVID-19(25) * - [x] Health Systems Implementation Initiative (HSII)(79) Health Systems Implementation Initiative (HSII)(79) * - [x] Health System Strategies to Address Disparities in Hypertension Management & Control(4) Health System Strategies to Address Disparities in Hypertension Management & Control(4) * - [x] Healthy Aging: Optimizing Physical and Mental Functioning(6) Healthy Aging: Optimizing Physical and Mental Functioning(6) * - [x] Implementation of Effective Shared Decision Making Approaches in Practice Settings(10) Implementation of Effective Shared Decision Making Approaches in Practice Settings(10) * - [x] Implementation of Findings from PCORI's Major Research Investments(2) Implementation of Findings from PCORI's Major Research Investments(2) * - [x] Implementation of PCORI-Funded Patient-Centered Outcomes Research Results (Limited PCORI Funding Announcement)(44) Implementation of PCORI-Funded Patient-Centered Outcomes Research Results (Limited PCORI Funding Announcement)(44) * - [x] Improving Healthcare Systems(114) Improving Healthcare Systems(114) * - [x] Improving Mental and Behavioral Health(5) Improving Mental and Behavioral Health(5) * - [x] Improving Methods for Conducting Patient-Centered Outcomes Research(186) Improving Methods for Conducting Patient-Centered Outcomes Research(186) * - [x] Improving Postpartum Maternal Outcomes for Populations Experiencing Disparities(5) Improving Postpartum Maternal Outcomes for Populations Experiencing Disparities(5) * - [x] Increasing COVID-19 Vaccine Confidence among Long-Term Care Workers: Expedited COVID-19 Targeted PCORI Funding Announcement (2021)(2) Increasing COVID-19 Vaccine Confidence among Long-Term Care Workers: Expedited COVID-19 Targeted PCORI Funding Announcement (2021)(2) * - [x] Infrastructure for Conducting Patient-Centered Comparative Clinical Effectiveness Research.

PCORnet®, the National Patient-Centered Clinical Research Network (Phase 4)(8) Infrastructure for Conducting Patient-Centered Comparative Clinical Effectiveness Research.

PCORnet®, the National Patient-Centered Clinical Research Network (Phase 4)(8) * - [x] Intellectual and Developmental Disabilities(5) Intellectual and Developmental Disabilities(5) * - [x] Limited Call for Proposals for HSII Implementation Projects (2023)(24) Limited Call for Proposals for HSII Implementation Projects (2023)(24) * - [x] Limited Competition PFA: Implementation Awards(5) Limited Competition PFA: Implementation Awards(5) * - [x] Limited PCORI 2016 Funding Announcement: Health Systems PCORnet Demonstration Project(4) Limited PCORI 2016 Funding Announcement: Health Systems PCORnet Demonstration Project(4) * - [x] Long-Term Follow-Up To Improve Patient-Centered Outcomes of PCORI-Funded CER(8) Long-Term Follow-Up To Improve Patient-Centered Outcomes of PCORI-Funded CER(8) * - [x] Management of Care Transitions for Emerging Adults with Sickle Cell Disease(2) Management of Care Transitions for Emerging Adults with Sickle Cell Disease(2) * - [x] Management Strategies for Treatment-Resistant Depression(3) Management Strategies for Treatment-Resistant Depression(3) * - [x] Managing Pain(1) Managing Pain(1) * - [x] Maternal Morbidity and Mortality(2) Maternal Morbidity and Mortality(2) * - [x] Medication-Assisted Treatment (MAT) Delivery for Pregnant Women with Substance Use Disorders Involving Prescription Opioids and/or Heroin(3) Medication-Assisted Treatment (MAT) Delivery for Pregnant Women with Substance Use Disorders Involving Prescription Opioids and/or Heroin(3) * - [x] Multimodal Interventions to Prevent Osteoporotic Fractures(3) Multimodal Interventions to Prevent Osteoporotic Fractures(3) * - [x] New Oral Anticoagulants (NOACs) in the Extended Treatment of Venous Thromboembolic Disease(3) New Oral Anticoagulants (NOACs) in the Extended Treatment of Venous Thromboembolic Disease(3) * - [x] Nonsurgical Options for Women with Urinary Incontinence(3) Nonsurgical Options for Women with Urinary Incontinence(3) * - [x] Obesity Observational Research Initiative(2) Obesity Observational Research Initiative(2) * - [x] Obesity Treatment Options Set in Primary Care for Underserved Populations(2) Obesity Treatment Options Set in Primary Care for Underserved Populations(2) * - [x] Observational Analyses of Second-Line Pharmacological Agents in Type 2 Diabetes(4) Observational Analyses of Second-Line Pharmacological Agents in Type 2 Diabetes(4) * - [x] Open Competition PFA: Implementation of Findings from PCORI's Research Investments(3) Open Competition PFA: Implementation of Findings from PCORI's Research Investments(3) * - [x] Optimal Maintenance Aspirin Dose for Patients with Coronary Artery Disease(1) Optimal Maintenance Aspirin Dose for Patients with Coronary Artery Disease(1) * - [x] Optimized Multidisciplinary Treatment Programs for Nonspecific Chronic Low Back Pain(1) Optimized Multidisciplinary Treatment Programs for Nonspecific Chronic Low Back Pain(1) * - [x] Optimizing Infrastructure for Conducting Patient-Centered Outcomes Research: PCORnet, The National Patient-Centered Clinical Research Network (Phase 3)(8) Optimizing Infrastructure for Conducting Patient-Centered Outcomes Research: PCORnet, The National Patient-Centered Clinical Research Network (Phase 3)(8) * - [x] Partnerships to Conduct Research within PCORnet (PaCR)(4) Partnerships to Conduct Research within PCORnet (PaCR)(4) * - [x] Partner Targeted PFA(4) Partner Targeted PFA(4) * - [x] Patient-Powered Research Network (PPRN) Research Demonstration Project: A Cross-PPRN Opportunity(1) Patient-Powered Research Network (PPRN) Research Demonstration Project: A Cross-PPRN Opportunity(1) * - [x] Patient-Powered Research Networks (PPRN) Research Demonstration Projects(6) Patient-Powered Research Networks (PPRN) Research Demonstration Projects(6) * - [x] PCOR for Treatment Options in Uterine Fibroids: Developing a Prospective Multi-Center Practice-based Clinical Registry (P50)(1) PCOR for Treatment Options in Uterine Fibroids: Developing a Prospective Multi-Center Practice-based Clinical Registry (P50)(1) * - [x] Pharmacologic and Nonpharmacologic Treatments for Migraine Prevention(2) Pharmacologic and Nonpharmacologic Treatments for Migraine Prevention(2) * - [x] Phased Large Awards for Comparative Effectiveness Research (PLACER)(26) Phased Large Awards for Comparative Effectiveness Research (PLACER)(26) * - [x] Pilot Projects(50) Pilot Projects(50) * - [x] Pragmatic Clinical Studies to Evaluate Patient-Centered Outcomes(48) Pragmatic Clinical Studies to Evaluate Patient-Centered Outcomes(48) * - [x] Prevention, Early Identification, and Treatment of Delirium in Older Adults(3) Prevention, Early Identification, and Treatment of Delirium in Older Adults(3) * - [x] Promoting Healthy Children and Youth(2) Promoting Healthy Children and Youth(2) * - [x] Psychosocial Interventions with Office-Based Opioid Treatment for Opioid Use Disorder(3) Psychosocial Interventions with Office-Based Opioid Treatment for Opioid Use Disorder(3) * - [x] Sleep Health(2) Sleep Health(2) * - [x] Strategies to Prevent Unsafe Opioid Prescribing in Primary Care among Patients with Acute or Chronic Non-Cancer Pain(3) Strategies to Prevent Unsafe Opioid Prescribing in Primary Care among Patients with Acute or Chronic Non-Cancer Pain(3) * - [x] Suicide Prevention: Brief Interventions for Youth(4) Suicide Prevention: Brief Interventions for Youth(4) * - [x] Symptom Management for Patients with Advanced Illness(2) Symptom Management for Patients with Advanced Illness(2) * - [x] Telehealth to Optimize Management of Multiple Chronic Conditions among Vulnerable Populations in Primary Care(5) Telehealth to Optimize Management of Multiple Chronic Conditions among Vulnerable Populations in Primary Care(5) * - [x] Testing Multi-Level Interventions to Improve Blood Pressure Control in Minority Racial/Ethnic, Low Socioeconomic Status, and/or Rural Populations (UH2/UH3)(2) Testing Multi-Level Interventions to Improve Blood Pressure Control in Minority Racial/Ethnic, Low Socioeconomic Status, and/or Rural Populations (UH2/UH3)(2) * - [x] The Effectiveness of Transitional Care(1) The Effectiveness of Transitional Care(1) * - [x] The Natural Experiments Network: A Collaborative Initiative(3) The Natural Experiments Network: A Collaborative Initiative(3) * - [x] Treatment of Anxiety in Children, Adolescents, and/or Young Adults(2) Treatment of Anxiety in Children, Adolescents, and/or Young Adults(2) * - [x] Treatment of Multiple Sclerosis(9) Treatment of Multiple Sclerosis(9) * - [x] Treatment of Posttraumatic Stress Disorder (PTSD) in Adults(2) Treatment of Posttraumatic Stress Disorder (PTSD) in Adults(2) * - [x] Treatment Options for Age-Related Hearing Loss(3) Treatment Options for Age-Related Hearing Loss(3) ### Health Condition More Information Health Conditions These are the broad terms PCORI's uses to categorize our funded research studies and other projects, journal articles on engagement in research, and engagement tools and resources.

Specific diseases/conditions are included within the appropriate larger category. Please note that not all of our funded studies focus on a single disease/condition. Some touch on multiple diseases/conditions, research methods, or broader health system interventions, so they won’t be listed by a primary disease/condition and may not appear if you use this filter tool to find them.

View GlossaryClose * - [x] Allergies and Immune Disorders(35) Allergies and Immune Disorders(35) * - [x] Allergies(4) Allergies(4) * - [x] Immune Disorders(22) Immune Disorders(22) * - [x] Lupus(3) Lupus(3) * - [x] Birth and Developmental Disorders(15) Birth and Developmental Disorders(15) * - [x] Blood Disorders(41) Blood Disorders(41) * - [x] Anemia(4) Anemia(4) * - [x] Sickle Cell Disease(25) Sickle Cell Disease(25) * - [x] Cancer(231) Cancer(231) * - [x] Anal Cancer(8) Anal Cancer(8) * - [x] Bladder Cancer(8) Bladder Cancer(8) * - [x] Brain Cancer(8) Brain Cancer(8) * - [x] Breast Cancer(44) Breast Cancer(44) * - [x] Cervical Cancer(15) Cervical Cancer(15) * - [x] Colorectal Cancer(32) Colorectal Cancer(32) * - [x] Intestinal Cancer(7) Intestinal Cancer(7) * - [x] Leukemia(7) Leukemia(7) * - [x] Liver Cancer(12) Liver Cancer(12) * - [x] Lung Cancer(33) Lung Cancer(33) * - [x] Ovarian Cancer(7) Ovarian Cancer(7) * - [x] Pancreatic Cancer(6) Pancreatic Cancer(6) * - [x] Prostate Cancer(22) Prostate Cancer(22) * - [x] Skin Cancer(7) Skin Cancer(7) * - [x] Uterine Cancer(6) Uterine Cancer(6) * - [x] Cardiovascular Diseases(233) Cardiovascular Diseases(233) * - [x] Atrial Fibrillation(13) Atrial Fibrillation(13) * - [x] Congestive Heart Failure(52) Congestive Heart Failure(52) * - [x] Coronary or Ischemic Heart Disease(48) Coronary or Ischemic Heart Disease(48) * - [x] Deep Vein Thrombosis/Pulmonary Embolism(10) Deep Vein Thrombosis/Pulmonary Embolism(10) * - [x] Hypertension(77) Hypertension(77) * - [x] Stroke(56) Stroke(56) * - [x] Dental Health(4) Dental Health(4) * - [x] Ear, Nose, and Throat Diseases(13) Ear, Nose, and Throat Diseases(13) * - [x] Ear Diseases(1) Ear Diseases(1) * - [x] Hearing Loss(7) Hearing Loss(7) * - [x] Throat Diseases(4) Throat Diseases(4) * - [x] Eye Diseases(5) Eye Diseases(5) * - [x] Functional Limitations and Disabilities(84) Functional Limitations and Disabilities(84) * - [x] Cognitive Difficulty(2) Cognitive Difficulty(2) * - [x] Independent Living Difficulty(1) Independent Living Difficulty(1) * - [x] Gastrointestinal Disorders(42) Gastrointestinal Disorders(42) * - [x] Crohn's Disease(10) Crohn's Disease(10) * - [x] Ulcerative Colitis(8) Ulcerative Colitis(8) * - [x] Ulcers(3) Ulcers(3) * - [x] Genetic Disorders(63) Genetic Disorders(63) * - [x] Infectious Diseases(126) Infectious Diseases(126) * - [x] Bacterial Infections(6) Bacterial Infections(6) * - [x] HIV/AIDS(28) HIV/AIDS(28) * - [x] Hospital Acquired Infections(4) Hospital Acquired Infections(4) * - [x] HPV and other Sexually Transmitted Infections(14) HPV and other Sexually Transmitted Infections(14) * - [x] Kidney Diseases(71) Kidney Diseases(71) * - [x] Chronic Kidney Disease(45) Chronic Kidney Disease(45) * - [x] Renal Failure(21) Renal Failure(21) * - [x] Liver Diseases(25) Liver Diseases(25) * - [x] Cirrhosis(6) Cirrhosis(6) * - [x] Hepatitis(11) Hepatitis(11) * - [x] Liver Failure(2) Liver Failure(2) * - [x] Mental/Behavioral Health(446) Mental/Behavioral Health(446) * - [x] Addiction/Substance Abuse(96) Addiction/Substance Abuse(96) * - [x] ADHD(14) ADHD(14) * - [x] Alcoholism(19) Alcoholism(19) * - [x] Anxiety(61) Anxiety(61) * - [x] Autism Spectrum Disorder(31) Autism Spectrum Disorder(31) * - [x] Bipolar Disorder(22) Bipolar Disorder(22) * - [x] Depression(132) Depression(132) * - [x] Eating and Feeding Disorders(4) Eating and Feeding Disorders(4) * - [x] Mild Cognitive Impairment(15) Mild Cognitive Impairment(15) * - [x] Post-Traumatic Stress Disorder(40) Post-Traumatic Stress Disorder(40) * - [x] Schizophrenia and Psychotic Disorders(19) Schizophrenia and Psychotic Disorders(19) * - [x] Serious Mental Illness(22) Serious Mental Illness(22) * - [x] Suicide(36) Suicide(36) * - [x] Tobacco Cessation(20) Tobacco Cessation(20) * - [x] Multiple/Comorbid Chronic Conditions(189) Multiple/Comorbid Chronic Conditions(189) * - [x] Muscular and Skeletal Disorders(95) Muscular and Skeletal Disorders(95) * - [x] Arthritis(43) Arthritis(43) * - [x] Chronic Back Pain(20) Chronic Back Pain(20) * - [x] Degenerative Muscular Disorders(4) Degenerative Muscular Disorders(4) * - [x] Disk Herniation/Nerve Compression(1) Disk Herniation/Nerve Compression(1) * - [x] Joint Replacement(9) Joint Replacement(9) * - [x] Osteoporosis/Osteopenia(9) Osteoporosis/Osteopenia(9) * - [x] Spinal Stenosis/Degenerative Lumbar Disorder(4) Spinal Stenosis/Degenerative Lumbar Disorder(4) * - [x] Neurological Disorders(181) Neurological Disorders(181) * - [x] Alzheimer's Disease(20) Alzheimer's Disease(20) * - [x] Cerebral Palsy(9) Cerebral Palsy(9) * - [x] Chronic Pain(40) Chronic Pain(40) * - [x] Dementia(27) Dementia(27) * - [x] Epilepsy(7) Epilepsy(7) * - [x] Hypo/Hyperthyroidism(2) Hypo/Hyperthyroidism(2) * - [x] Migraine(6) Migraine(6) * - [x] Multiple Sclerosis(22) Multiple Sclerosis(22) * - [x] Parkinson's Disease(11) Parkinson's Disease(11) * - [x] Nutritional and Metabolic Disorders(176) Nutritional and Metabolic Disorders(176) * - [x] Diabetes(131) Diabetes(131) * - [x] Obesity(56) Obesity(56) * - [x] Other or Non-Disease Specific(133) Other or Non-Disease Specific(133) * - [x] Rare Diseases(141) Rare Diseases(141) * - [x] Reproductive and Perinatal Health(142) Reproductive and Perinatal Health(142) * - [x] Contraceptive Care(9) Contraceptive Care(9) * - [x] Neonatal Care(7) Neonatal Care(7) * - [x] Pregnancy and Birth Outcomes(58) Pregnancy and Birth Outcomes(58) * - [x] Uterine Fibroids and Cysts(6) Uterine Fibroids and Cysts(6) * - [x] Respiratory Diseases(172) Respiratory Diseases(172) * - [x] Asthma(42) Asthma(42) * - [x] Chronic Obstructive Pulmonary Disease(43) Chronic Obstructive Pulmonary Disease(43) * - [x] Pulmonary Fibrosis(4) Pulmonary Fibrosis(4) * - [x] Respiratory Infections(45) Respiratory Infections(45) * - [x] Sleep Apnea(15) Sleep Apnea(15) * - [x] Skin Diseases(13) Skin Diseases(13) * - [x] Psoriasis(4) Psoriasis(4) * - [x] Toxins(3) Toxins(3) * - [x] Trauma/Injuries(64) Trauma/Injuries(64) * - [x] Falls(8) Falls(8) * - [x] Fractures(9) Fractures(9) * - [x] Head Injury(14) Head Injury(14) * - [x] Occupational Injury(2) Occupational Injury(2) * - [x] Physical Abuse(7) Physical Abuse(7) * - [x] Spinal Cord Injury(6) Spinal Cord Injury(6) * - [x] Urinary Disorders(27) Urinary Disorders(27) * - [x] Incontinence(14) Incontinence(14) * - [x] Urinary Tract Infections(5) Urinary Tract Infections(5) * - [x] Wellness(16) Wellness(16) * - [x] Immunizations(3) Immunizations(3) ### Intervention Strategy More Information Intervention Strategies The intervention strategies being implemented by the research study, such as drug intervention, behavioral intervention, etc. Used only for research studies.

These tags are added to a study award page a couple of months after they have been funded.

View GlossaryClose * - [x] Behavioral Interventions(255) Behavioral Interventions(255) * - [x] Complementary and Alternative Medicine(42) Complementary and Alternative Medicine(42) * - [x] Device Interventions(66) Device Interventions(66) * - [x] Drug Interventions(234) Drug Interventions(234) * - [x] Incentives for Behavior Change(17) Incentives for Behavior Change(17) * - [x] Other Clinical Interventions(261) Other Clinical Interventions(261) * - [x] Care Coordination(186) Care Coordination(186) * - [x] Patient Navigation(63) Patient Navigation(63) * - [x] Shared Decision Making(57) Shared Decision Making(57) * - [x] Telemedicine(113) Telemedicine(113) * - [x] Other Health Services Interventions(482) Other Health Services Interventions(482) * - [x] Policy Interventions(24) Policy Interventions(24) * - [x] Screening Interventions(62) Screening Interventions(62) * - [x] Technology Interventions(296) Technology Interventions(296) * - [x] Training and Education Interventions(468) Training and Education Interventions(468) ### Year Awarded More Information Year Awarded The year PCORI approved the research study or project for funding.

View GlossaryClose * - [x] 2012(75) 2012(75) * - [x] 2013(237) 2013(237) * - [x] 2014(107) 2014(107) * - [x] 2015(271) 2015(271) * - [x] 2016(315) 2016(315) * - [x] 2017(281) 2017(281) * - [x] 2018(151) 2018(151) * - [x] 2019(185) 2019(185) * - [x] 2020(149) 2020(149) * - [x] 2021(186) 2021(186) * - [x] 2022(166) 2022(166) * - [x] 2023(188) 2023(188) * - [x] 2024(176) 2024(176) * - [x] 2025(158) 2025(158) * - [x] 2026(39) 2026(39) * - [x] 2014(58) 2014(58) * - [x] 2015(41) 2015(41) * - [x] 2016(112) 2016(112) * - [x] 2017(214) 2017(214) * - [x] 2018(414) 2018(414) * - [x] 2019(190) 2019(190) * - [x] 2020(140) 2020(140) * - [x] 2021(202) 2021(202) * - [x] 2022(136) 2022(136) * - [x] 2023(159) 2023(159) * - [x] 2024(90) 2024(90) * - [x] 2025(139) 2025(139) * - [x] 2026(50) 2026(50) Displaying 1 - 25 of 2685 results ### [Pharmacologic and Nonpharmacologic Treatments for Post-Traumatic Stress Disorder (PTSD) [Systematic Reviews]](https://www.

pcori.

org/research-results/2026/pharmacologic-and-nonpharmacologic-treatments-ptsd-systematic-reviews) To be posted upon completion ### Food As Medicine Strategies in the Health System University of Southern California (USC) ### Visualizing Gene Therapy Evidence Through a Construction of a Dashboard ### Surgical Treatment of Adults With Degenerative Lumbar Spinal Stenosis (A Systematic Review) To be posted upon completion ### Pragmatic Trial Comparing the Effectiveness of a Systems-Level Patient Plus Clinician Intervention to Either Alone To Improve Advance Care Planning Implementation Among Older Adults in Primary Care Awarded; Contract pending ### Implementation of Telepsychiatry Collaborative Care for Complex Psychiatric Disorders: University Hospitals University Hospitals Cleveland Medical Center Awarded; Contract pending Implementation Project (HSII) ### A National Comparative Effectiveness Analysis of Two Dementia Care Interventions in Communities University of Minnesota-Twin Cities Joseph Gaugler, M.

S. , Ph. D.

Awarded; Contract pending ### Implementation of Telepsychiatry Collaborative Care for Complex Psychiatric Disorders: Atrium Health Wake Forest University Health Sciences Awarded; Contract pending Implementation Project (HSII) ### Randomized Controlled Trial of Trauma-Focused Cognitive Behavioral Therapy and Common Elements Treatment Approach to Treat Trauma and Comorbid Problems in Youth Johns Hopkins University Bloomberg School of Public Health Laura Murray, M.

A. , Ph. D.

Awarded; Contract pending ### Implementation of Electronic Patient-Reported Outcomes Monitoring During Cancer Treatment: Queen’s Medical Center The Queen's Medical Center Awarded; Contract pending Implementation Project (HSII) ### Implementation of Electronic Patient-Reported Outcomes Monitoring During Cancer Treatment: UCSF The Regents of the University of California, San Francisco Rafael Gonzales, M. D. , M.

S. Awarded; Contract pending Implementation Project (HSII) ### Implementation of Effective Hypertension Management Approaches: San Francisco Health Network San Francisco Health Network Awarded; Contract pending Implementation Project (HSII) ### Comparing Two Multicomponent Strategies To Promote Sleep and Reduce Delirium in Adults in Intensive Care Units Biren Kamdar, M. D.

, M. S. , MHS, MBA Awarded; Contract pending ### Modality Choice Before and After Failure for the Treatment of Painful Diabetic Neuropathy Regents of the University of Michigan Brian Callaghan, M.

D. , M. S.

Awarded; Contract pending ### Improving Consent for Patient-Centered Research With Adults With Intellectual Disability Katherine McDonald, Ph. D. Awarded; Contract pending ### Alternative Approaches for Managing Blood Pressure in Children With Chronic Kidney Disease The Children's Hospital of Philadelphia Michelle Denburg, M.

D. , MSCE Awarded; Contract pending ### Beyond Per-Protocol Effects: Improving Study Designs To Maximize Patient Choice The University of Texas MD Anderson Cancer Center Kerollos Wanis, M. D.

, Ph. D. , M.

S.

Awarded; Contract pending ### Implementation of Effective Hypertension Management Approaches: Jefferson Health Awarded; Contract pending Implementation Project (HSII) ### Implementation of Effective Hypertension Management Approaches: MedStar Health MedStar Health Research Institute Awarded; Contract pending Implementation Project (HSII) ### Comparative Effectiveness of Two Dementia Caregiver Support Interventions for Depressive Symptoms Johns Hopkins University Bloomberg School of Public Health Lauren Parker, Ph.

D. , MPH Awarded; Contract pending ### Modeling and Decision Making With Complex Longitudinal Healthcare Data Johns Hopkins University Bloomberg School of Public Health Awarded; Contract pending ### Comparative effectiveness and safety of antinausea medications in pregnancy Kaiser Foundation Research Institute, a Division of Kaiser Foundation Hospitals Sascha Dublin, M. D.

, Ph. D.

Awarded; Contract pending ### Comparing Two Approaches to Delivering Treatment to Youth With Trauma and Substance Use Medical University of South Carolina Awarded; Contract pending ### Implementation of Effective Hypertension Management Approaches: Mercy Health Awarded; Contract pending Implementation Project (HSII) ### Implementation of Effective Hypertension Management Approaches: CommonSpirit Health Awarded; Contract pending Implementation Project (HSII) Get weekly updates about opportunities to apply for funding, newly funded research and engagement projects, results of PCORI-funded research, webinars and other news.

1333 New Hampshire Avenue NW, Suite 1200 Phone: (202) 827-7700 | Fax: (202) 355-9558 * Frequently Asked Questions * Trademark Usage Guidance