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The Genesis Mission: Transforming Science and Energy with AI is sponsored by U.S. Department of Energy (DOE) Office of Science, Biological and Environmental Research (BER). This program supports AI-enhanced climate and earth system modeling and technologies in four areas, including 'Scaling the Biotechnology Revolution.'
Proposals advancing biotechnology, especially those with strong commercial potential and alignment with DOE's mission, are encouraged.
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Or search similar grants →Extracted from the funder's website rather than a specific solicitation. Confirm program details with the funder.
The Genesis Mission | Department of Energy A national initiative to build the world’s most powerful scientific platform. The Genesis Mission unites DOE National Labs, industry, academia, and more to harness AI for breakthroughs in energy dominance, discovery science, and national security. Inside the Genesis Mission The Genesis Mission is turning vision into action.
Building a national AI-for-science ecosystem. Advancing new partnerships. Developing cutting-edge capabilities.
All to accelerate scientific discovery. Addressing National Science and Technology Challenges in Key Areas DOE has identified national science and technology challenges to accelerate U.S. innovation and leadership. These challenges will deliver tangible benefits for the American people through the Genesis Mission’s AI platforms and partnerships.
American Science and Security Platform The American Science and Security Platform The Genesis Mission will build a complex integrated platform, connecting the world’s best supercomputers, experimental facilities, AI systems, and unique datasets.
Collaboration and Consortium Bringing Together World-Class Innovators The Genesis Mission brings together cross-sector and cross-functional leading experts to solve critical challenges at unprecedented speed. Learn More about Genesis Collaboration and Consortium In March 2026, DOE announced funding to advance the Genesis Mission’s efforts to tackle the nation’s most complex science and technology challenges.
Get details on the Request for Applications here: The Genesis Mission: Transforming Science and Energy with AI .
U.S. Department of Energy Announces More Than $800 Million in Partner Commitments to the Genesis Mission Secretary of Energy Chris Wright Announces First Genesis Mission Projects Selected to Accelerate AI-Driven Scientific Discovery United States and Japan Announce Historic $1 Billion Partnership Under President Trump’s Genesis Mission From CSIS: Betting on America | Can AI Accelerate Scientific Discovery?
Featuring Under Secretary Darío Gil From PowerMag: The Genesis Mission: How AI Supercomputing Is About to Reshape American Science and Energy Energy Department Announces $293 Million in Funding to Support Genesis Mission National Science and Technology Challenges Energy Department Launches ‘Genesis Mission’ to Transform American Science and Innovation Through the AI Computing Revolution Get Genesis Mission updates from the Under Secretary for Science.
Explore the Genesis Mission Genesis Mission National Science and Technology Challenges The American Science and Security Platform Genesis Mission Collaboration Office of the Under Secretary for Science Genesis Mission University Summit Report Genesis Mission Workforce Development RFI Summary Genesis Mission RFA Awards List Get Genesis Mission Updates Follow Under Secretary Gil on LinkedIn Follow Under Secretary Gil on X
According to the current listing, eligibility includes: DOE National Laboratories, other Federal Agencies (check eligibility), and potentially other domestic applicants like Minority-Serving Institutions and emerging research institutions. Confirm the full requirements on the funder's own website before applying.
The current listing shows $5,000 - $5,000,000. Verify award ceilings, matching requirements, and allowable costs on the funder's own website.
Applications for The Genesis Mission: Transforming Science and Energy with AI are due December 17, 2026. Build your timeline backwards from this date to cover registrations, approvals, and final submission checks.
The Genesis Mission: Transforming Science and Energy with AI is funded by U.S. Department of Energy (DOE) Office of Science, Biological and Environmental Research (BER). Verify program details on the funder's own website before applying.
Start from the funder's website linked on this page and look for its grants or funding section — the link goes to the funder's site rather than a specific solicitation.
Past winners and funding trends for this program
DE-FOA-0003665, the Office of Science Open Call, accepts applications any day until September 30, 2027. But six program offices run their own comparative review panels on their own dates, and a proposal that arrives after a panel's acceptance date waits a year. Here is how to read the hidden calendar.
Read articleThe Trump administration committed $5B and 278 projects across 15+ agencies to the Genesis Mission. Here's the structure — and how to position for the next wave.
Read articleOn July 22, 2026, the White House announced more than $5 billion in federal commitments for the Genesis Mission — the Department of Energy-led national initiative to fuse AI, exascale computing, and the 17 national labs into a single scientific platform. Nearly 300 projects across all 50 states were selected from a historic Request for Applications, and 15-plus agencies are now attaching funding to a set of National Science and Technology Challenges. Here is what the Genesis Mission is, how the money is structured, and the concrete on-ramps for researchers, universities, and small businesses who were not in the first cohort.
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