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Find similar grantsThe Genesis Mission: Transforming Science and Energy with AI is sponsored by U.S. Department of Energy (DOE) Office of Science (SC) - Advanced Scientific Computing Research (ASCR). This funding opportunity focuses on accelerating a new era of AI-driven scientific discovery, relevant to the Department of Energy's mission.
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Opportunity Listing - The Genesis Mission: Transforming Science and Energy with AI The Genesis Mission: Transforming Science and Energy with AI Agency: Office of Science Assistance Listings: 81. 049 -- Office of Science Financial Assistance Program Last Updated: May 13, 2026 View version history on Grants.
gov DOE is soliciting new FY26 Phase I small team and Phase II large team applications in the following topic areas: advanced manufacturing, biotechnology, critical materials, nuclear fission, nuclear fusion, quantum information science, semiconductors and microelectronics, discovery science, and energy (see specific focus areas in Section III Program Descriptions).
In addition, this RFA will remain available to allow the recipients of FY26 Phase I awards to apply for larger team Phase II awards. In a few weeks, DOE plans to amend the RFA to clarify the LOI and application guidelines for FY26 Phase II awards.
In FY27, DOE plans to amend the RFA or to issue an alternative funding opportunity to update the topic and focus areas to allow a second competition of Phase I small team applications and Phase II large team applications. Grantor contact information GenesisMissionNOFO@science. doe.
gov GenesisMissionNOFO@science. doe. gov GenesisMissionNOFO@science.
doe. gov File name Description Last updated Genesis_Mission_Phase_I_Application_Template_v2. xlsx Phase I Application Template Apr 10, 2026 01:23 PM UTC Genesis_Mission_Phase_II_LOI_Template_v2.
xlsx Phase II LOI Template Apr 10, 2026 01:23 PM UTC Sample_OT_and_Project_Agreements_for_DE-FOA-0003612_REV2. pdf Sample OT and Project Agreements Jul 20, 2026 01:23 PM UTC Genesis_Mission_Phase_II_Application_Template. xlsx Phase II Application Template Apr 10, 2026 01:24 PM UTC DE-FOA-0003612.
000003. pdf DE-FOA-0003612 Apr 20, 2026 09:28 PM UTC Link to additional information Closing: December 17, 2026 Funding opportunity number : Cost sharing or matching requirement : Funding instrument type : Opportunity Category Explanation : Category of Funding Activity : Science technology and other research and development Your account requires additional identity verification.
According to the current listing, eligibility includes: Open to academic institutions, the private sector, and other non-profit organizations as well as government labs. Confirm the full requirements in the official notice before applying.
Applications for The Genesis Mission: Transforming Science and Energy with AI are due December 17, 2026. Build your timeline backwards from this date to cover registrations, approvals, and final submission checks.
The Genesis Mission: Transforming Science and Energy with AI is funded by U.S. Department of Energy (DOE) Office of Science (SC) - Advanced Scientific Computing Research (ASCR). Verify program details on the funder's official page before applying.
Yes — this listing is flagged as national in scope, so applicants across the U.S. may apply, subject to the sponsor's other eligibility criteria.
Applications go through the funder's official portal — the Apply Now link on this page goes there directly.
The DOE Genesis Mission offers $293M for AI-driven research across 20+ fields from quantum science to nuclear energy. Phase I applications due April 28, 2026.
Read articleThe Department of Energy is investing $145M in early career researchers and $68M in AI for science simultaneously. Together, these programs reveal a deliberate strategy to build an AI-literate research pipeline — and the application windows are open now.
Read articleThe Trump administration committed $5B and 278 projects across 15+ agencies to the Genesis Mission. Here's the structure — and how to position for the next wave.
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