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DOE Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Phase I Genesis Mission Opportunity is sponsored by U.S. Department of Energy (DOE). This opportunity supports small businesses in developing innovative technologies with strong commercial potential, specifically aligning with the Genesis Mission's goals to advance American leadership in artificial intelligence.
This includes projects supporting topics like scaling the biotechnology revolution, realizing quantum systems for discovery, designing materials with predictable functionality, and achieving AI-driven autonomous laboratories.
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DOE Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) | Department of Energy DOE Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Light Text on a Dark Overlay (Default) The U.S. Department of Energy’s Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs are competitive non-dilutive funding programs that support American small businesses in developing innovative technologies with strong commercial potential.
The DOE recently consolidated the management of the SBIR/STTR programs to the Office of Technology Commercialization (OTC), reflecting DOE’s focus on moving taxpayer-funded research toward real-world impact. The SBIR/STTR programs align directly with OTC’s mission to accelerate commercialization, streamline innovation pathways, and strengthen engagement between small businesses and the DOE National Laboratory system.
This transition reinforces DOE’s commitment to improving operational efficiency and investing in technological advancements towards energy dominance. Additional resources and program information will be added to this site as program updates are finalized. SBIR and STTR are congressionally authorized programs that reserve a portion of federal research funding for U.S. small businesses.
Through a competitive, phased process, companies receive funding to establish technical feasibility (Phase I), further develop and prototype their technology (Phase II), and pursue commercialization and follow-on opportunities (Phase III). Participation is limited to for-profit U.S. small businesses that meet Small Business Administration eligibility requirements.
DOE coordinates its SBIR/STTR implementation with the U.S. Small Business Administration. The Small Business Innovation and Economic Security Act (S. 3971) was signed into law on April 13, 2026.
This Act extends the SBIR/STTR Programs through Fiscal Year 2031. FY26 Phase I Genesis Mission Opportunity DOE announced the opening of the FY26 Phase I Genesis Mission SBIR/STTR opportunity on July 22, 2026.
These projects will support an anticipated 40 awards across the following four Genesis Mission-focused topic areas: Scaling the Biotechnology Revolution Realizing Quantum Systems for Discovery: AI for Quantum Computing and Networking Designing Materials with Predictable Functionality Achieving AI-Driven Autonomous Laboratories This initial release precedes a broader Phase I funding opportunity expected later this fall.
FY25 Phase II Opportunity DOE’s new SBIR/STTR programs will follow the phases illustrated below. Participants will submit a single application to enter the program and may progress to subsequent phases through a series of Go/No-Go decision points. Therefore, once the initial application is submitted, no additional applications will be required.
Instead, participants will advance through subsequent phases at their own pace by successfully meeting established milestones and performance criteria. Will SBIR/STTR opportunities be open for applications in 2026?
DOE has several planned SBIR-STTR announcements this year: Opening for applications to Phase II topics Opening for applications to some Phase I topics Opening for applications to additional Phase I topics I have a currently active project. Will it be impacted by the program management transition to OTC? No, currently active projects will not be impacted by this change.
All projects awarded prior to March 2026 will continue under the same points of contact. I have an active Phase I project. Will I have the opportunity to apply for a Phase II award?
Yes, recipients of Phase I awards will be able to apply for Phase II awards. Stay tuned for updates by subscribing to the OTC SBIR/STTR newsletter . What technology areas do the DOE SBIR/STTR programs support?
DOE SBIR/STTR topics are drawn from the mission areas of the Department. DOE offers opportunities annually. Future SBIR/STTR opportunities will address national challenges in advanced manufacturing, biotechnology, critical materials, quantum information science, semiconductors, energy innovation, and more.
What is the difference between SBIR and STTR? The SBIR program was established by Congress in 1982 [Public Law 97-219].
It major goals are to: Stimulate technological innovation Use small business to meet Federal R/R&D needs Increase private sector commercialization of innovations derived from Federal R/R&D, thereby increasing competition, productivity, and economic growth The STTR program was established by Congress in 1992 [Public Law 102-564].
Its major goals are to: Stimulate and foster scientific and technological innovation through cooperative research and development carried out between small business concerns and research institutions Foster technology transfer between small business concerns and research institutions How can I share my feedback about the SBIR and STTR programs? DOE is committed to continuous program improvement.
You can email SBIR and STTR program feedback and recommendations to sbir-sttr@hq. doe. gov .
Are there other DOE opportunities that can support the development or commercialization of my energy technology? American Made Challenges incentivizes innovation through prizes, training, teaming, and mentoring, connecting the nation’s entrepreneurs and innovators to America’s national labs and the private sector.
ConnectWerx administers critical energy opportunities to heighten energy security and strengthen national security ecosystems. EnergyWerx facilitates discovery, engagement, and acceleration of energy innovation to strengthen national security and energy resiliency. TechWerx is a hub that connects visionaries, researchers, industry and energy leaders with the opportunities for technological advancement.
SBIR/STTR Applicant Resources Key resources for applicants to the DOE SBIR/STTR programs. SBIR/STTR Applicant Resources Reporting Fraud: SBIR/STTR An overview on combating, understanding, and reporting SBIR/STTR fraud. Reporting Fraud: SBIR/STTR Required SBIR/STTR Registrations There are three essential registrations that small businesses must complete to apply for an SBIR or STTR award.
Required SBIR/STTR Registrations Security Risk Management: SBIR/STTR In the SBIR and STTR Extension Act of 2022 and the Small Business Innovation and Economic Security Act of 2026, Congress established requirements for Federal agencies to create a due diligence program to assess security risks in the SBIR/STTR programs.
Security Risk Management: SBIR/STTR Commercialization Resources Commercialization is a central goal of the DOE SBIR/STTR programs. This page lists resources to help foster success. Commercialization Resources SBIR/STTR Program Policy Factors Program policy factors may be considered in determining funding recipients, in addition to the expert scores and comments.
SBIR/STTR Program Policy Factors Building a Winning SBIR/STTR Team The team that the small business assembles for their SBIR/STTR application is crucial and should demonstrate to the reviewers that the applicant has the necessary expertise, experience, and ability to carry out the proposed project. Building a Winning SBIR/STTR Team SBIR/STTR Phase III Guidance Phase III awards are fundamentally different from Phase I and II awards.
SBIR/STTR Phase III Guidance
According to the current listing, eligibility includes: For-profit U.S. small businesses that meet Small Business Administration eligibility requirements. Applicants must submit a Project Pitch. Confirm the full requirements in the official notice before applying.
The current listing shows anticipated 40 awards, amount not specified but Phase I typically up to $200,000. Verify award ceilings, matching requirements, and allowable costs in the official notice.
Applications for DOE Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Phase I Genesis Mission Opportunity are due September 10, 2026. Build your timeline backwards from this date to cover registrations, approvals, and final submission checks.
DOE Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Phase I Genesis Mission Opportunity is funded by U.S. Department of Energy (DOE). Verify program details on the funder's official page before applying.
Yes — this listing is flagged as national in scope, so applicants across the U.S. may apply, subject to the sponsor's other eligibility criteria.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
Past winners and funding trends for this program
NVIDIA Graduate Fellowship Program is a grant from NVIDIA providing up to $60,000 per award to PhD students conducting research that advances accelerated computing and its applications. Now in its 25th year, the program invites nominations from doctoral students pushing the boundaries of artificial intelligence, robotics, autonomous vehicles, and related fields. Recipients receive not only research funding but also access to NVIDIA technology, products, and engineering expertise, along with a mandatory in-person summer internship. Students are nominated by their faculty advisors and selected based on academic achievement and research area alignment.
CalSEED Concept Award is a grant from the California Energy Commission that provides $150,000 in funding to early-stage clean energy innovators in California. The program targets individuals, businesses, and nonprofits developing hardware, software, or integrated solutions at Technology Readiness Levels 2-4. Eligible technology areas rotate each cycle and have included battery recycling and reuse, long-duration energy storage, medium- and heavy-duty vehicle electrification, industrial electrification, and advanced EV charging. Applicants must be located in California, have under $1 million in private funding, and propose innovations that benefit California ratepayers. Concept Award winners also receive professional development resources and access to accelerator programs, and may compete for a subsequent $450,000 Prototype Award.
The Trump administration committed $5B and 278 projects across 15+ agencies to the Genesis Mission. Here's the structure — and how to position for the next wave.
Read articleIn January 2026, DOE Policy Flash PF-2026-30 wiped out every 15% and 10% indirect cost cap the administration had imposed in 2025 — because H.R. 6938 ordered it to. The same law froze indirect policy at NSF, Commerce and NASA. But OMB's sweeping new grants rule quietly reopens the fight through the back door. Here is what changed, what money recipients can claw back, and how to protect your indirect recovery going forward.
Read articleOn July 22, 2026, the Department of Energy opened the first Phase I SBIR/STTR release tied to its Genesis Mission — roughly 40 awards across biotechnology, AI-for-quantum, predictable-materials design, and autonomous laboratories — alongside about $147M in FY25 Phase II funding. Here is what each topic area actually wants, who is eligible, how this connects to the $5B Genesis Mission, and how a small business should position before the broader fall solicitation.
Read article